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  1. Immunoglobulin A nephropathy (IgAN) is one of the most common forms of primary glomerulonephritis (GN) worldwide. While specific treatment differs regionally, treatment usually focuses on background therapy, w...

    Authors: Sarah N. Ali, Nicole Fusco, Dilip Makhija, Vakaramoko Diaby, Tosin Oladapo, Darsh Devani, Cibele Pinto, Mohit Mathur and Ancilla W. Fernandes
    Citation: BMC Nephrology 2025 26:249
    Content type: Research Published on:

  2. This study aimed to develop and validate a nomogram to predict the risk of peritoneal dialysis-associated peritonitis (PDAP) in patients undergoing peritopreneal dialysis.

    Authors: Yuehong Wang, Zhimin Wu, Liuqi Huang, Dan Suo, Min Zhang, Meifen Dai, Tianhui You and Jing Zheng
    Citation: BMC Nephrology 2025 26:248
    Content type: Research Published on:

  3. Maintenance hemodialysis (MHD) patients often suffer from sarcopenia, affecting lower limb muscle strength and increasing the risk of falls and mortality. This study aims to develop an auxiliary screening mode...

    Authors: Yujie Yang, Hualong Liao, Yang Chen, Ying Qiu, Fei Yan, Ping Fu, Jirong Yue, Yu Chen and Huaihong Yuan
    Citation: BMC Nephrology 2025 26:247
    Content type: Research Published on:

  4. While the appearance of red clots in the dialyzer and the arterial and venous blood tubing lines is a common phenomenon in every hemodialysis unit, the occurrence of recurrent yellowish-white matter formation ...

    Authors: Weijuan Lou, Yongchun Xi, Ya Liu, Xueling Cai, Junfang Gai, Jianyong Yin, Jiahui Ding, Yifang Yang, Yanjuan Teng, Tingfang Chen, Niansong Wang and Yongping Guo
    Citation: BMC Nephrology 2025 26:246
    Content type: Case Report Published on:

  5. Type 2 diabetes (T2DM) is the leading cause of chronic kidney disease (CKD) worldwide. Identifying clinical and laboratory associations with chronic kidney disease (CKD) in type 2 diabetes (T2DM) can help phys...

    Authors: Ajay Kumar, Anirban Mazumdar, A. K. Bhattacharjee, Arvind Gupta, Arundhati Dasgupta, Binayak Sinha, Banshi Saboo, Chitra Selvan, Ghanshyam Goyal, Jaganmohan Balaji, Krishna G. Seshadri, Kalyan K. Gangopadhyay, G. Vijay Kumar, Manoj Chawla, Mohua Sikdar, Nilakshi Deka…
    Citation: BMC Nephrology 2025 26:245
    Content type: Research Published on:

  6. Oxidative stress is a driver of acute and chronic kidney injury. Selonsertib is a clinical stage antagonist of ASK1 (MAP3K5), a serine/threonine kinase that is a mediator of oxidative stress signaling pathways...

    Authors: Vladimir Petrovic, Andrew Whiteman, Matt Peach, Sam Kim, Vladislav A. Malkov, Grant Budas and Andrew N. Billin
    Citation: BMC Nephrology 2025 26:244
    Content type: Research Published on:

  7. Stress-induced hyperglycemia (SIH) is a common phenomenon in acute myocardial infarction and is associated with poor prognosis. The relationship between glycemic gap (GG), a marker of SIH, and ST-segment eleva...

    Authors: Xiaofu Zhang, Yong Li, Qinghuan Yang, Siwen Wu, Yang Song, Ziyun Luo and Jianping Xu
    Citation: BMC Nephrology 2025 26:243
    Content type: Research Published on:

  8. Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent monogenic polycystic kidney disorder, but ADPKD presented as Glomerulocystic kidney (GCK) in adults is uncommon. Thin basement membrane...

    Authors: Wenji Wang, Lin Chen, Feng Ding and Xuezhu Li
    Citation: BMC Nephrology 2025 26:242
    Content type: Case Report Published on:

  9. Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that can lead to end organ damage and death without treatment. The ability to rapidly distinguish aHUS from other forms of TMA is...

    Authors: Miguel G. Uriol-Rivera, Frank R. Ernst, John N. Booth III, Àngels Comas, Christoph Gasteyger, Ioannis Tomazos, Ching Lum, Yan Wang and Ana I. Ávila
    Citation: BMC Nephrology 2025 26:241
    Content type: Research Published on:

  11. Authors: Debasish Kar, Richard Byng, Aziz Sheikh, Mintu Nath, Bedowra Zabeen, Shubharthi Kar, Shakila Banu, Mohammad Habibur Rahman Sarker, Navid Khan, Durjoy Acharjee, Shafiqul Islam, Victoria Allgar, José M. Ordóñez-Mena, Aya El-Wazir, Soon Song, Ashish Verma…
    Citation: BMC Nephrology 2025 26:239
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2025 26:168

  12. C3 Glomerulopathy (C3G) is an ultra-rare glomerular disease driven by dysregulation of the alternative pathway of complement. 30–50% of adult patients progress to end stage kidney disease (ESKD) within 10 year...

    Authors: Lauren O. Fergus, Meryl Waldmann, Monica D. Hall, Lynn Vining, Jillian Hall, Tina Liu, Yuzhou Zhang, Patrick J. Walker, Richard J. H. Smith and Carla M. Nester
    Citation: BMC Nephrology 2025 26:238
    Content type: Research Published on:

  13. Nephrotic syndrome (NS) is a common kidney disorder in children, characterized by significant proteinuria, hypoalbuminemia, and peripheral edema. While glucocorticoids (GCs) are the first-line treatment for pe...

    Authors: Sarranya Paranthaman, Priyanka Srivastava, Anu Kumari, Chitra Bhardwaj, Pratibha Bawa, Anupriya Kaur, Inusha Panigrahi, Lesa Dawman and Karalanglin Tiewsoh
    Citation: BMC Nephrology 2025 26:237
    Content type: Research Published on:

  14. The CKD in PLHIV is highly prevalent in Jalisco. Despite its control with ART, HIV is characterized by generating low-grade inflammation events that contribute to the development and progression of CKD. Consid...

    Authors: Andrea Torres-Rojas, Luz Alicia González-Hernández, Karina Sánchez-Reyes, Jonathan Samuel Chávez-Iñiguez, Jorge Fernando Topete-Reyes, Jaime Federico Andrade-Villanueva, Pedro Martínez-Ayala, Adriana Valle-Rodriguez, Vida Verónica Ruiz-Herrera, Jorge Hernández-Bello, Zyanya Reyes-Castillo and Monserrat Álvarez-Zavala
    Citation: BMC Nephrology 2025 26:236
    Content type: Research Published on:

  15. Neutrophil extracellular traps (NETs) and oxidative stress (OS) may be involved in sepsis-associated acute kidney injury (SA-AKI). The aim of this study was to identify potential regulators which modulate NETs...

    Authors: Tang Shaoqun, Yu Xi, Wang Wei, Luo Yaru, Lei Shaoqing, Qiu Zhen, Yang Yanlin, Sun Qian and Xia Zhongyuan
    Citation: BMC Nephrology 2025 26:235
    Content type: Research Published on:

  16. Chronic Kidney disorders is a global public health problem, including in women with polycystic ovarian syndrome (PCOS), and is characterized by renal fibrosis, nephrotoxicity and glomerulonephritis, which incr...

    Authors: Stephanie E. Areloegbe, Chukwubueze L. Atuma, Ayodeji Aturamu, Isaac O. Ajadi, Oluseyi E. Adelekan, Mary B. Ajadi, Christopher O. Akintayo, Gloria O. Omoruyi, Samuel O. Onyekweli, Omosola F. Anifowose, Oluwatobi A. Amusa, Kayode Ajayi, Paul A. Oyewole, Tolulope E. Adegoke and Kehinde S. Olaniyi
    Citation: BMC Nephrology 2025 26:234
    Content type: Research Published on:

  17. Thrombotic microangiopathy (TMA) represents a broad spectrum of diseases. The combination of TMA with lupus nephritis (LN) is associated with worse renal outcomes and a higher mortality rate. To date, there is...

    Authors: Ahmed Fayed, Rasmia Elgohary, Amr Mohamed Shaker, Karem Mohamed Salem, Eman El Desouky and Gehad Gamal Maghraby
    Citation: BMC Nephrology 2025 26:233
    Content type: Research Published on:

  18. Urinary tract infections (UTIs) are the most prevalent infections among kidney transplant recipients, with recurrent cases imposing a significant financial burden due to increased hospitalizations and treatmen...

    Authors: Hany M. El Hennawy, Omar Safar, Mahmoud Z. El Madawie, Jayson Gopiechand, Ibrahim Tawhari, Weam El Nazer, Mohammad F. Zaitoun and Abdullah S. Al Faifi
    Citation: BMC Nephrology 2025 26:232
    Content type: Research Published on:

  19. Patients with chronic kidney disease (CKD) have a high prevalence of cerebrovascular disease and cognitive impairment. The objective was to analyse whether plasma concentrations of neurofilament light chain (N...

    Authors: Torunn Axelsson, Henrik Zetterberg, Kaj Blennow, Burak Arslan, Nicholas J. Ashton, Markus Axelsson, Maria K. Svensson, Aso Saeed and Gregor Guron
    Citation: BMC Nephrology 2025 26:231
    Content type: Research Published on:

  21. Infections in renal transplant recipients (RTRs) carry great risk of morbidity-mortality, and the risk of graft loss. Concomitant infections, although common in immunosuppressed patients, should be highly susp...

    Authors: Andrade Sierra Jorge, Carvallo-Venegas Mauricio, Andrade-Ortega Antonio de Jesús, Andrade-Ortega Jorge, Cerrillos-Gutiérrez José Ignacio, Aguilar-Fletes Laura Elizabeth, Briseño-Hernández Andres Alejandro and Carrasco-Carrizosa Aldo
    Citation: BMC Nephrology 2025 26:229
    Content type: Case Report Published on:

  23. Hyperkalemia is a frequent life-threatening condition in hemodialysis (HD) patients. Data comparing the usage of various K + binders in HD patients is still scarce. This study aimed to compare the efficacy and...

    Authors: Mohamed Mamdouh Elsayed, Marwa Ahmed Abdelrahman, Abdelrazik Mohamed Sorour, Islam Ghanem Rizk and Mohamed Aly Abdelhalim Hassab
    Citation: BMC Nephrology 2025 26:227
    Content type: Research Published on:

  24. Fatigue among patients with end-stage kidney disease (ESKD) undergoing hemodialysis significantly impacts quality of life and anticipated treatment results. This study explores how Omani patients undergoing he...

    Authors: Zakariya Al-Naamani, Kevin Gormley, Helen Noble, Olinda Santin, Omar Al Omari, Huda Al-Noumani and Norah Madkhali
    Citation: BMC Nephrology 2025 26:226
    Content type: Research Published on:

  25. Living donor kidney transplantation (LDKT) is a complex medical procedure requiring extensive education for both donors and transplant candidates. With technological advances in healthcare, video educational r...

    Authors: Tayler E. Truhan, James McMahon, Aisling E. Courtney, Paul Gill, Holly Mansell, Helen Noble, Joanne Reid, Nicola Rosaasen, Alison Wood and Clare McKeaveney
    Citation: BMC Nephrology 2025 26:225
    Content type: Research Published on:

  26. To evaluate the effectiveness of a Shared Decision-Making (SDM) program in reducing unplanned dialysis among patients with advanced chronic kidney disease (CKD) and to identify factors predictive of unplanned ...

    Authors: Pannawat Mongkolrattanakul and Kittiphan Chienwichai
    Citation: BMC Nephrology 2025 26:224
    Content type: Research Published on:

  28. End-stage renal disease (ESRD) is associated with significant morbidity and mortality, with patients often experiencing micronutrient deficiencies due to dialysis treatments. Hemodiafiltration with Endogenous ...

    Authors: Changhao Zhu, Lingling Ding, Naiying Lan, Fanzhou Zeng, Dan Ye, Hao Wang and Bo Yang
    Citation: BMC Nephrology 2025 26:222
    Content type: Study Protocol Published on:

  29. Due to a shortage of cadaveric organs for transplantation, some Saudi patients seek to purchase kidneys in other countries. However, kidney transplantation (KT) abroad is often associated with negative outcome...

    Authors: Hany M. El Hennawy, Omar Safar, Abdullah S. Al Faifi, Maryam H. El Hennawy, Balqees Alghamdi, Amani Ali, Manar Alqahtani, Mohammad F. Zaitoun, Sharifah A. Alasmari, Ahmed Serageldeen, Konstantinos Fourtounas, Mostafa Ayyad, Ahmed Ali and Mohamed H. Zahran
    Citation: BMC Nephrology 2025 26:221
    Content type: Research Published on:

  30. When an adult patient lacks decision-making capacity, care decisions must be made on their behalf in their “best interests”. We know little about the experiences of the family members of adult kidney patients ...

    Authors: Jordan A. Parsons, Fergus J. Caskey and Jonathan Ives
    Citation: BMC Nephrology 2025 26:220
    Content type: Research Published on:

  31. This is a scoping review of the evidence for the use of the Patient Self-Management Assessment Tool for Hypertension (PAT) in people with hypertension. This review examines the content features, reliability, a...

    Authors: Li Mengjiao, Zhao Xujie, Jiang Ping, Huang Liwen, Ning Yuping, Zhang Yangjing and Yan Jianjun
    Citation: BMC Nephrology 2025 26:219
    Content type: Research Published on:

  32. Herpes- and polyomaviruses are major opportunistic pathogens after renal transplantation. Despite established guidelines, there is limited data on transplant centers’ prophylaxis and monitoring strategies and ...

    Authors: Claudia Sommerer, Iris Schröter, Katrin Gruneberg, Daniela Schindler, Christian Morath, Lutz Renders, Gunilla Einecke, Martina Guthoff, Uwe Heemann, Paul Schnitzler, Martin Zeier and Thomas Giese
    Citation: BMC Nephrology 2025 26:218
    Content type: Research Published on:

  33. Hyperlactatemia is common in intensive care unit (ICU) patients. The aim of our retrospective observational study was to analyse the impact of serum lactate on admission on mortality in patients with acute kid...

    Authors: Robert Ekart, Barbara Kobal, Tea Korošec, Eva Jakopin, Franc Svenšek, Nejc Piko, Sebastjan Bevc and Radovan Hojs
    Citation: BMC Nephrology 2025 26:217
    Content type: Research Published on:

  35. Low physical activity (LPA) is a major contributor to the global burden of chronic kidney disease (CKD). Our goal was to assess the spatiotemporal trends in the CKD burden attributable to LPA from 1990 to 2021...

    Authors: ZhenYi Zhao, Jing Mi, HaoDong Jin, ShuaiRan Li and Xia Bai
    Citation: BMC Nephrology 2025 26:215
    Content type: Research Published on:

  36. Maintenance hemodialysis patients experience high morbidity and mortality, primarily from cardiovascular and infectious diseases. It was discovered recently that low arterial oxygen saturation (SaO2) is associate...

    Authors: Hanjie Zhang, Andrea Nandorine Ban and Peter Kotanko
    Citation: BMC Nephrology 2025 26:214
    Content type: Research Published on:

  37. Potassium binders mitigate hyperkalemia, allowing patients to maintain their renin-angiotensin-aldosterone-system inhibitor (RAASi) treatment. This study characterized patients treated with first- or second-ge...

    Authors: Hans Furuland, Anders Olof Larsson, Per Bjellerup, Milica Uhde, Thomas Cars, Matilda Almstedt and Maria K. Svensson
    Citation: BMC Nephrology 2025 26:213
    Content type: Research Published on:

  38. Post-traumatic growth is regarded as a screening indicator for quality of life of hemodialysis patients. Interpersonal relationships and forgiveness of hemodialysis patients may play an important role in impro...

    Authors: Yansheng Ye, Qin Xie, Yane Sun, Jianqing Xu, Linan Cheng and Linglin Kong
    Citation: BMC Nephrology 2025 26:212
    Content type: Research Published on:

  39. Chronic kidney disease (CKD), hypertension, and diabetes are associated with dementia, and insulin resistance promotes vascular dysfunction resulting in dementia. However, the study of insulin use in preventin...

    Authors: Yun-Yi Chen, Yi-Hsien Chen, Yu-Wei Fang, Jing-Tong Wang and Ming-Hsien Tsai
    Citation: BMC Nephrology 2025 26:211
    Content type: Research Published on:

  40. Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular risk, elevated morbidity and mortality rates, reduced quality of life, and high medical costs. Self-care behavio...

    Authors: Mella Riski, Irma Melyani Puspitasari, Cherry Rahayu and Sofa D. Alfian
    Citation: BMC Nephrology 2025 26:210
    Content type: Research Published on:

  41. Persistent controversies surround the treatment of Immunoglobulin A nephropathy (IgAN), necessitating the exploration of safer and more effective therapeutic agents. Tripterygium wilfordii, a traditional Chine...

    Authors: Yanping Wu, Ruman Chen, Danfang Deng, Wenjing Wu and Xiaoqin Wang
    Citation: BMC Nephrology 2025 26:209
    Content type: Research Published on:

  42. Sepsis-associated acute kidney injury (AKI) presents a significant clinical challenge, necessitating the identification of predictive indicators for early detection and intervention. This retrospective case-co...

    Authors: Daofeng Huang, Zhaobin Yang, Luzhen Qiu, Jinzhan Lin and Xiaomei Cheng
    Citation: BMC Nephrology 2025 26:208
    Content type: Research Published on:

  43. Emphysematous pyelonephritis (EPN) is a necrotizing infection characterized by the production of gas in the renal parenchyma, collecting system or perirenal tissue. The treatment strategy, especially for surgi...

    Authors: Ukyo Yamamoto, Motoka Yagame, Daisuke Uchida, Masumi Hara, Hideyuki Takeuchi and Hiroo Kawarazaki
    Citation: BMC Nephrology 2025 26:207
    Content type: Case Report Published on:

  44. The incidence of clear cell renal cell carcinoma (ccRCC) has steadily increased over the past decade, and recent studies have linked bile acid (BA) metabolism to its development. However, the metabolic profile...

    Authors: Qi-Chao Wang, Jing-Yi Cao, Guang-Yue Wang, Heng Wang, Hua Peng, Qian Wang, Zhi-Xiang Yin, Jie-Zhou, Ping-An Chang, Gui-Hua Zhang, Wen-Tao Yao, Jia-Cheng Wu and Chang-Song Pei
    Citation: BMC Nephrology 2025 26:206
    Content type: Research Published on:

  45. In critically ill elderly patients, malnutrition is a common comorbidity. The Geriatric Nutritional Risk Index (GNRI) is a straightforward tool for evaluating the nutritional status of elderly individuals. The...

    Authors: Kailun Cai, Wenchao Mao, Mingkun Yang, Changqin Chen, Shijin Gong, Lifen Zheng and Changyun Zhao
    Citation: BMC Nephrology 2025 26:205
    Content type: Research Published on:

  46. Kidney failure is associated with a high symptom burden, yet few studies describe real-world management approaches.

    Authors: Kurinji Nalankilli, Elizabeth Stallworthy, Kathryn Ducharlet, Barnaby D. Hole, Daniel V. O’Hara, Neeru Agarwal, Charlotte M. Snead, Fergus J. Caskey and Brendan Smyth
    Citation: BMC Nephrology 2025 26:204
    Content type: Research Published on:

  47. Hospital readmission following renal transplantation significantly impacts patient outcomes and healthcare resources. While machine learning approaches offer promising solutions for risk prediction, their clin...

    Authors: Nasser Alnazari, Omar Ibrahim Alanazi, Muath Owaidh Alosaimi, Ziyad Mohamed Alanazi, Ziyad Mohammed Alhajeri, Khaled Mohammed Alhussaini, Abdulkarim Mekhlif Alanazi and Ahmed Y. Azzam
    Citation: BMC Nephrology 2025 26:203
    Content type: Research Published on:

  48. In patients undergoing hemodialysis, functional dependence has increasingly been recognized as a critical factor influencing both quality of life and clinical outcomes. This study evaluates the combined effect...

    Authors: Rong Ni, Peng Qian, Ci Sun, Yusheng Xu, Kai Song and Weiwei Li
    Citation: BMC Nephrology 2025 26:202
    Content type: Research Published on:

  50. Changes in lipid levels over time and the associated all-cause mortality have not yet been studied in different populations of patients undergoing dialysis. This study aimed to investigate the differences in t...

    Authors: Zhenjian Xu, Yuchun Zeng, Yingyan Liang, Xuefeng Xie, Xiaomei Li, Qiongqiong Yang and Peifen Liang
    Citation: BMC Nephrology 2025 26:199
    Content type: Research Published on:
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BMC Nephrology

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