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  1. This study aimed to explore the specific efficacy of rituximab (RTX) in the treatment of membranous nephropathy (MN) and compare and analyze the differences in effectiveness among various treatment regimens, w...

    Authors: Xiaolong Wang, Xueying Cao, Jie Wu, Shuang Liang, Jian Yang and Hong Wang
    Citation: BMC Nephrology 2025 26:49
    Content type: Research Published on:

  2. Patients treated with chronic dialysis or kidney transplantation have difficulties in maintaining employment. We aimed to estimate employment rates among dialysis and kidney transplant patients from 3 years be...

    Authors: Rasmus Kirkeskov Carlsen, Lilli Kirkeskov, Margit S. Riis, Rikke K. Jacobsen, Frederikke Hørdam Gronemann, Merete Osler, Janne Petersen and Niels Henrik Buus
    Citation: BMC Nephrology 2025 26:48
    Content type: Research Published on:

  3. Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consuming and not availabl...

    Authors: Antoine Lanot, Anna Akesson, Felipe Kenji Nakano, Celine Vens, Jonas Björk, Ulf Nyman, Anders Grubb, Per-Ola Sundin, Björn O. Eriksen, Toralf Melsom, Andrew D. Rule, Ulla Berg, Karin Littmann, Kajsa Åsling-Monemi, Magnus Hansson, Anders Larsson…
    Citation: BMC Nephrology 2025 26:47
    Content type: Research Published on:

  5. Ursodeoxycholic acid (UDCA), traditionally recognized for its hepatoprotective effects, has also shown potential in protecting kidney injury. This study aimed to evaluate the protective effects of UDCA against...

    Authors: Yunpeng Lou, Hongguang Shi, Ning Sha, Feifei Li, Xiaofeng Gu and Huiyan Lin
    Citation: BMC Nephrology 2025 26:45
    Content type: Research Published on:

  7. Limited studies have explored the relationship between estimated Glomerular Filtration Rate(eGFR) and in-hospital mortality(IHM) in low-income sub-Saharan African countries. This study aimed to explores this a...

    Authors: Odong Christopher, Wang Yanmei, Makabayi Emmanuel Yeko, Doreen Mary Nanyunja and Kuule Julius Kabbali
    Citation: BMC Nephrology 2025 26:43
    Content type: Research Published on:

  8. People with chronic kidney disease are at increased risk of thrombotic and bleeding episodes making anticoagulant treatment decisions challenging. Currently, there are no support tools for people with chronic ...

    Authors: Kathrine Parker, Abigail Needham, Jecko Thachil, Sandip Mitra and Penny Lewis
    Citation: BMC Nephrology 2025 26:42
    Content type: Research Published on:

  9. The high prevalence and prolonged duration of inflow pain and drain pain experienced by peritoneal dialysis (PD) patients following PD catheter implantation impact their quality of life. However, there is limi...

    Authors: Shun Hua, Peiyi Cao, Guanji Zhang, Guanglan Li, Simin Jiang, Yiping Xu, Jianbo Li, Jianwen Yu, Naya Huang, Jianxiong Lin, Xiao Yang, Wei Chen, Haiping Mao and Zhong Zhong
    Citation: BMC Nephrology 2025 26:41
    Content type: Research Published on:

  10. This study aims to investigate the relationship between urinary creatinine (UCr) and the risk and severity of Diabetic Kidney Disease (DKD) in patients with Type 2 Diabetes Mellitus (T2DM). The goal is to esta...

    Authors: Huihong Cao, Li Song, Xiaojun Wang and Haochen Guan
    Citation: BMC Nephrology 2025 26:40
    Content type: Research Published on:

  11. One million patients are estimated to have undiagnosed chronic kidney disease (CKD) in England. Clinical coding in CKD is associated with improved management and lower acute kidney injury (AKI), unscheduled ca...

    Authors: Samantha Dolan, Ajitesh Anand, Philip A. Kalra and Stuart Stewart
    Citation: BMC Nephrology 2025 26:39
    Content type: Research Published on:

  12. Diabetes treatments by the control of sodium-glucose cotransporter 2 (SGLT2) is commonly conducted while there are still uncertainties about the mechanisms for the SGLT2 overexpression in kidneys with diabetes...

    Authors: Aiko Seki, Koichiro Kajiwara, Jumpei Teramachi, Masahiko Egusa, Takuya Miyawaki and Yoshihiko Sawa
    Citation: BMC Nephrology 2025 26:38
    Content type: Research Published on:

  13. Chronic kidney disease (CKD) is a prevalent global health issue affecting millions of patients worldwide, impacting quality of life, impeding physical and psychological well-being, causing financial stress, an...

    Authors: Mohammed A. Alshehri, Husain Y. Alkhlady, Zuhier A. Awan, Mohammed Ridha Algethami, Hadiah B. Al Mahdi, Hussam Daghistani and Khalid Orayj
    Citation: BMC Nephrology 2025 26:37
    Content type: Research Published on:

  14. Physical performance is low and physical activity declines in people with chronic kidney disease (CKD). Both factors are associated with decreased survival. Our hypothesis was that improved physical performanc...

    Authors: Sara Denguir, Matthias Hellberg, Martin Almquist and Naomi Clyne
    Citation: BMC Nephrology 2025 26:36
    Content type: Research Published on:

  15. Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and depression is also a common mental health issue in this population. Despite the prevalenc...

    Authors: Xiaohua Hu, Xianwu Ye, Haimin Chen, Bibo Wu, Qi Guo, Chen Yu, Wei Ding, Jianying Niu, Junli Zhao, Hualin Qi, Suhua Zhang, Cheng Xue and Liming Zhang
    Citation: BMC Nephrology 2025 26:35
    Content type: Research Published on:

  16. Hypertension and chronic kidney disease (CKD) are interconnected conditions that can significantly affect a person’s health-related quality of life (HRQoL). In low- and middle-income countries (LMICs), this di...

    Authors: Wening Wulandari, Neily Zakiyah, Cherry Rahayu, Irma M. Puspitasari and Auliya A. Suwantika
    Citation: BMC Nephrology 2025 26:34
    Content type: Review Published on:

  17. Kidney transplantation (kTx) is by far the most effective method of treating end-stage renal disease, with immunosuppressive therapy being obligatory for all, except identical twins. Despite kTx being the most...

    Authors: Aleksandra Anna Kajdas, Marcin Kleibert, Anne Katrine Normann, Krzysztof Krasuski, Ditte Søndergaard Linde and Dorota Szostak-Węgierek
    Citation: BMC Nephrology 2025 26:33
    Content type: Research Published on:

  18. IgA nephropathy (IgAN) exhibits an unpredictable trajectory, creating difficulties in prognostication, monitoring, treatment, and research planning. This study provides a comprehensive depiction of the progres...

    Authors: Mariell Rivedal, Ole Petter Nordbø, Yngvar Lunde Haaskjold, Rune Bjørneklett, Thomas Knoop and Øystein Eikrem
    Citation: BMC Nephrology 2025 26:32
    Content type: Research Published on:

  19. A number of UK transplantation centres use isotope studies to estimate the relative contribution from each kidney in living kidney donor assessment. The evidence that the estimation of pre-donation split funct...

    Authors: Kirsty J. Crowe, Siobhan K. McManus, Julie A. Glen, Karen S. Stevenson, Ian M. McLaughlin, Alice Nicol and Colin C. Geddes
    Citation: BMC Nephrology 2025 26:31
    Content type: Research Published on:

  20. High blood pressure is a prevalent condition in patients with chronic kidney disease on hemodialysis. Adequate control of high blood pressure is essential to reducing deaths in this group. The present study ai...

    Authors: Franklin Geovany Mora-Bravo, Pamela Tatiana Morales Torres, Nelson Rojas Campoverde, Guillermina Lucía Blum Carcelen, Juan Cristobal Santacruz Mancheno, Ángel Cristóbal Santacruz Tipanta, Hector Perez-Grovas and Willan Patricio Robles Abarca
    Citation: BMC Nephrology 2025 26:30
    Content type: Research Published on:

  21. This study aimed to explore the clinical and pathological features of patients with diabetic kidney disease (DKD), with and without non-diabetic kidney disease (NDKD), through a retrospective analysis. The obj...

    Authors: Mengjie Jiang, Hongyu Chen, Jing Luo, Jinhan Chen, Li Gao and Qin Zhu
    Citation: BMC Nephrology 2025 26:29
    Content type: Research Published on:

  22. The existing criteria for living kidney donors (LKDs)in Japan are controversial. We evaluated the roles of computed tomography volumetry (CTV) and 99 m Tc-diethylenetriamine penta-acetic acid (DTPA) scintigrap...

    Authors: Shunta Hori, Mitsuru Tomizawa, Kuniaki Inoue, Tatsuo Yoneda, Kenta Onishi, Yosuke Morizawa, Daisuke Gotoh, Yasushi Nakai, Makito Miyake, Kazumasa Torimoto, Nobumichi Tanaka and Kiyohide Fujimoto
    Citation: BMC Nephrology 2025 26:28
    Content type: Research Published on:

  23. Kidney transplantation is the preferred treatment for patients with end-stage renal disease, significantly preserving kidney function and patient quality of life. However, post-transplant diabetes mellitus (PT...

    Authors: Dominika Macakova, Josef Zadrazil, David Karasek, Veronika Kucerova, Katerina Langova and Lubica Cibickova
    Citation: BMC Nephrology 2025 26:27
    Content type: Research Published on:

  24. Exploring the risk factors for mortality of hemodialysis patients undergoing COVID-19 and the changes in mortality before and after the opening of the epidemic in northern Hunan province, China.

    Authors: Zhangxiu He, Zhong Peng, Ning Gao, Shuzhu Zhong, Fengyi Yu, Zixu Tang, Zihao Liao, Song Zhao, Gloria Umwiza, Ming Chen and Wei Long
    Citation: BMC Nephrology 2025 26:26
    Content type: Research Published on:

  25. Nephrology referral has been recognized as a modifiable factor influencing patient outcomes. The study aimed to compare clinical outcomes among patients referred early versus late to nephrologists.

    Authors: Linan Cheng, Nan Hu, Di Song, Li Liu and Yuqing Chen
    Citation: BMC Nephrology 2025 26:25
    Content type: Research Published on:

  26. The factors influencing diffuse crescentic glomerulonephritis renal survival and prognosis remain uncertain. Additionally, there’s no literature on the clinical outcomes of IgA nephropathy, lupus nephritis, an...

    Authors: Shan Wen, Shasha Chen, Yingying Lin, Guisen Li, Ping Zhang and Wei Wang
    Citation: BMC Nephrology 2025 26:24
    Content type: Research Published on:

  27. Rhabdomyolysis is frequently associated with acute kidney injury (AKI). Due to the nephrotoxic properties of myoglobin, its rapid removal is relevant. If kidney replacement therapy (KRT) is necessary for AKI, ...

    Authors: Lorenz Weidhase, Antonia Borrmann, Anja Willenberg, Meinhard Mende, Christina Scharf-Janßen, Sirak Petros and Jonathan de Fallois
    Citation: BMC Nephrology 2025 26:23
    Content type: Research Published on:

  28. Chronic Kidney Disease (CKD) has emerged as a global public health concern. People with the most advanced stage of CKD require renal replacement therapies, either dialysis (the focus of this study) or a kidney...

    Authors: Maya Annie Elias, Wim Van Damme, Grace Marie V Ku, Mahesh Kadammanavar and Edwin Wouters
    Citation: BMC Nephrology 2025 26:22
    Content type: Research Published on:

  29. The impact of chronic kidney disease (CKD) on healthy life expectancy and healthcare costs requires research. This study examined associations between CKD and healthy life expectancy, and its economic burden.

    Authors: Hisayuki Ogura, Tadashi Toyama, Hikaru Samuta, Kohei Hirako, Tomoya Itatani, Shiori Nakagawa, Megumi Oshima, Shinji Kitajima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Tomoyuki Takura, Takashi Wada and Yasunori Iwata
    Citation: BMC Nephrology 2025 26:21
    Content type: Research Published on:

  30. Gut dysbiosis characterized by an imbalance in pathobionts (Enterobacter, Escherichia and Salmonella) and symbionts (Bifidobacterium, Lactobacillus and Prevotella) can occur during chronic kidney disease (CKD) pr...

    Authors: Inès Obolo Nwaga, Victorine Bandolo Nzana, Rhoda Nsen Bughe, Isaac Dah, Cheboh Cho-Fon, Maimouna Mahamat, Emmanuelle Ndjong, Aristide Nono, Jean Claude Mballa, Fon Abongwa Acho, Vicky Ama Moor, Wilfred Fon Mbacham and François Folefack Kaze
    Citation: BMC Nephrology 2025 26:20
    Content type: Research Published on:

  31. Effective treatment of late antibody-mediated rejection (late AMR) is still an unmet medical need. Clearing donor-specific antibody (DSA) and preventing its rebound is the ideal goal of treatment.

    Authors: Zhiliang Guo, Rula Sa, Daqiang Zhao, Songxia Li, Hui Guo, Lan Zhu and Gang Chen
    Citation: BMC Nephrology 2025 26:19
    Content type: Research Published on:

  33. Cardiac surgery is a major contributor to acute kidney injury (AKI); approximately 22% of patients who undergo cardiac surgery develop AKI, and among them, 2% will require renal replacement therapy (RRT). AKI ...

    Authors: Fatma Refaat Ahmed, Nabeel Al-Yateem, Seyed Aria Nejadghaderi, Rawia Gamil and Mohannad Eid AbuRuz
    Citation: BMC Nephrology 2025 26:17
    Content type: Research Published on:

  36. Accurate assessment of fluid volume and hydration status is essential in many disease states, including patients with chronic kidney disease. The aim of this study was to investigate the ability of a wearable ...

    Authors: Frida Bremnes, Cecilia Montgomery Øien, Jørn Kvaerness, Ellen Andreassen Jaatun, Sigve Nyvik Aas, Terje Saether, Henrik Lund and Solfrid Romundstad
    Citation: BMC Nephrology 2025 26:14
    Content type: Research Published on:

  37. Dialysis recovery time (DRT) refers to the period during which fatigue and weakness subside following hemodialysis treatment, allowing patients to resume their daily routines. This study aimed to identify the ...

    Authors: Nurten Ozen, Tayfun Eyileten, Paulo Teles, Baris Seloglu, Ayse Gurel, Aysegul Ocuk, Volkan Ozen, Filipa Fernandes, Luís Campos, Sara Coutinho, Joana Teixeira, Sandra Cristina Mendo Moura, Olga Ribeiro and Clemente Neves Sousa
    Citation: BMC Nephrology 2025 26:13
    Content type: Research Published on:

  38. The effects of acute kidney injury (AKI) on liver-related outcomes in patients with hepatitis B virus (HBV) infection remain unclear. The study aimed to evaluate the association between AKI with liver-related ...

    Authors: Jiao Liu, Ruixuan Chen, Shiyu Zhou, Zhixin Guo, Licong Su, Lisha Cao, Yanqin Li, Xiaodong Zhang, Fan Luo, Ruqi Xu, Qi Gao, Yuxin Lin, Xin Xu and Sheng Nie
    Citation: BMC Nephrology 2025 26:12
    Content type: Research Published on:

  41. Results from the CONVINCE clinical trial suggest a 23% mortality risk reduction among patients receiving high-volume (> 23 L) hemodiafiltration. We assessed the real-world effectiveness of blood-based kidney r...

    Authors: Yan Zhang, Anke Winter, Belén Alejos Ferreras, Paola Carioni, Otto Arkossy, Michael Anger, Robert Kossmann, Len A. Usvyat, Stefano Stuard and Franklin W. Maddux
    Citation: BMC Nephrology 2025 26:9
    Content type: Research Published on:

  42. Chronic kidney disease (CKD) is a global health problem, affecting over 840 million individuals. CKD is linked to higher mortality and morbidity, partially mediated by higher cardiovascular risk and worsening ...

    Authors: Christoph Wanner, Johannes Schuchhardt, Chris Bauer, Meike Brinker, Frank Kleinjung and Tatsiana Vaitsiakhovich
    Citation: BMC Nephrology 2025 26:8
    Content type: Research Published on:

  43. Infectious episodes contribute to morbidity and mortality in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Renal involvement, also known as ANCA-associated glomerulonep...

    Authors: Li-Li Long, Mei Tan, Hui Deng, Hui Tang, Xiao-Qing Lin, Miao Zhang, Hui-Ying Deng and Xia Gao
    Citation: BMC Nephrology 2025 26:7
    Content type: Research Published on:

  44. Patients with end-stage renal disease usually undergo hemodialysis as a way of renal function replacement therapy which comes with a wide array of systemic and cutaneous complications. The aim of this study wa...

    Authors: Mohammad Hassan Al-thnaibat, Heba M. Urabi, Hadeel S. Alkofahi, Ola Mohannad Alshriedeh, Raneem Alshraideh, Hanan Esmadi, Ahmed Sheyyab, Bakri Roumi Jamal and Hanan Khaled Hasan
    Citation: BMC Nephrology 2025 26:6
    Content type: Research Published on:

  45. The prevalence of chronic kidney disease (CKD) is estimated to be about 13.4% worldwide. Studies have shown that CKD accounts for up to 2% of the health cost burden. Various factors, such as genetic polymorphi...

    Authors: Samaneh Madani, Seyed Jalil Masoumi, Afsane Ahmadi, Morteza Zare, Najmeh Hejazi and Sahar Foshati
    Citation: BMC Nephrology 2025 26:5
    Content type: Research Published on:

  46. Continuous ambulatory peritoneal dialysis (CAPD) is one of the kidney replacement therapy (KRT) modalities used in patients with kidney failure. It is the preferred modality in most resource-limited settings a...

    Authors: Tshifhiwa B. Sikhipha, Claire Barrett, Nicoline van Zyl, Cornel van Rooyen and Feziwe B. Bisiwe
    Citation: BMC Nephrology 2025 26:4
    Content type: Research Published on:

  47. To investigate the current status of medication adherence among peritoneal dialysis (PD) patients in a primary hospital and to explore the influencing factors of medication adherence among PD patients.

    Authors: Chen Ling, Yuxia Ouyang, Jiaqi Cao, Jingwen Bi and Yunfang Zhang
    Citation: BMC Nephrology 2025 26:3
    Content type: Research Published on:

  48. The 2019 Kidney Disease Outcome Quality Initiative guidelines emphasize the importance of selecting dialysis based on the life expectancy of the patient. However, it is difficult to predict the life expectancy...

    Authors: Hyo Kee Kim, Heungman Jun and Sun-Young Ko
    Citation: BMC Nephrology 2025 26:2
    Content type: Research Published on:

  49. The problem of reduced physical activity in patients with stage 5 Chronic Kidney Disease (CKD) is becoming more and more interesting in the medical community. One of the innovative solutions that can significa...

    Authors: Agnieszka Turoń-Skrzypińska, Alicja Mińko, Aleksandra Rył, Aneta Cymbaluk-Płoska, Maciej Domański, Kazimierz Ciechanowski and Iwona Rotter
    Citation: BMC Nephrology 2025 26:1
    Content type: Research Published on:

  50. The impact of protein-bound uremic toxins, specifically indoxyl sulfate (IS) on peritoneal dialysis (PD) complications remains controversial. This study aimed to explore the link between serum total IS (tIS) l...

    Authors: Natalia Stepanova, Victoria Driianska, Lesya Korol and Lyudmyla Snisar
    Citation: BMC Nephrology 2024 25:475
    Content type: Research Published on:
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BMC Nephrology

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