Table 4 Association of steroid toxicity with SNP rs10482634
From: NR3C1 variants and glucocorticoid response in childhood nephrotic syndrome in North India
rs10482634 | Chi-square value | p-value | |||
|---|---|---|---|---|---|
AA (wild) | AG (hetero) | GG (mutant) | |||
Weight gain | 15 | 6 | 5 | 8.397 | 0.015 |
Short stature | 8 | 1 | 4 | 8.397 | 0.015 |
Cataract | 7 | 3 | 1 | 0.921 | 0.631 |
Glaucoma | 1 | 1 | 1 | 1.363 | 0.506 |
Hypertension | 34 | 24 | 8 | 0.228 | 0.892 |
Hyperglycaemia | 1 | 0 | 1 | 3.231 | 0.199 |
Cushingoid facies | 36 | 18 | 10 | 7.898 | 0.019 |
Acanthosis | 7 | 4 | 1 | 0.42 | 0.81 |
Immunosuppression | 1 | 1 | 0 | 0.322 | 0.851 |
Gastritis | 9 | 5 | 1 | 0.872 | 0.646 |
Hirsutism | 13 | 8 | 4 | 0.787 | 0.675 |