Table 3 Association of rs10482634 and rs6877893 with steroid resistance
From: NR3C1 variants and glucocorticoid response in childhood nephrotic syndrome in North India
SNPs | Genotype | SSNS group N (%) | SRNS group N (%) | Chi-square value | OR 95% CI | p-value |
|---|---|---|---|---|---|---|
rs10482634 | AA (wild) | 29 (58.0%) | 21 (42.0%) | 6.613 | 0.037* | |
AG (hetero) | 19 (38.0%) | 19 (38.0%) | 1.381(0.59–3.22) | |||
GG (mutant) | 2 (4.0%) | 10 (20.0%) | 6.905(1.36–34.8) | |||
rs6877893 | AA (wild) | 19 (38.0%) | 15 (30.0%) | 2.066 | - | 0.356 |
GA (hetero) | 22 (44.0%) | 20 (40.0%) | 1.15(0.46–2.8) | |||
GG (mutant) | 9 (18.0%) | 15 (30.0%) | 2.1(0.72–6.14) |