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Table 5 Association between risk factors and 60-day mortality in ICU patients with AKI and IHD (N = 29) using univariate and multivariate Cox-regression analysis

From: Hyperlactatemia in critically ill patients with acute kidney injury treated with renal replacement therapy in the intensive care unit

Risk factors

 

60-day mortality

  
 

Univariate

 

Multivariate

 
 

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value

Age

1.142 (1.058–1.234)

< 0.001

1.094 (1.001–1.195)

0.047

Gender

0.902 (0.321–2.535)

0.846

-

-

Hypertension

0.729 (0.211–2.523)

0.618

-

-

Diabetes

0.535 (0.207–1.386)

0.198

-

-

CKD

0.788 (0.280–2.218)

0.652

1.746 (0.450–6.773)

0.450

Serum lactate (mmol/L)

1.158 (0.989–1.357)

0.069

1.003 (0.854–1.178)

0.973

CRP (mg/L)

0.999 (0.994–1.003)

0.559

-

-

eGFR (mL/min/1.73m2)

0.990 (0.974–1.007)

0.259

-

-

CCI

1.671(1.304–2.140)

< 0.001

1.594 (1.141–2.228)

0.006

SOFA

1.002 (0.866–1.159)

0.977

-

-

APACHE II

1.040 (0.988–1.093)

0.132

-

-

  1. Abbreviations: APACHE II, Acute Physiologic Assessment and Chronic Health Evaluation II; CCI, Charlton morbidity index; CKD, chronic kidney disease; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; SOFA Sepsis-related Organ Failure Assessment
  2. Bold values are statistically significant with the value < 0.05