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Table 4 Association between risk factors and 60-day mortality in ICU patients with AKI and CRRT (N = 125) using univariate and multivariate Cox-regression analysis

From: Hyperlactatemia in critically ill patients with acute kidney injury treated with renal replacement therapy in the intensive care unit

Risk factors

 

60-day mortality

  
 

Univariate

 

Multivariate

 
 

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value

Age

1.028 (1.011–1.044)

< 0.001

1.022 (0.996–1.047)

0.096

Gender

1.147 (0.747–1.760)

0.531

-

-

Hypertension

0.808 (0.530–1.233)

0.324

-

-

Diabetes

0.845 (0.569–1.254)

0.403

-

-

CKD

0.568 (0.351–0.919)

0.021

0.619 (0.353–1.088)

0.096

Serum lactate (mmol/L)

1.057 (0.992–1.127)

0.089

1.050 (0.986–1.118)

0.125

CRP (mg/L)

0.998 (0.997-1.000)

0.063

-

-

eGFR (mL/min/1.73m2)

0.999 (0.993–1.006)

0.876

-

-

CCI

1.171(1.073–1.279)

< 0.001

1.042 (0.898–1.208)

0.590

SOFA

0.991 (0.924–1.063)

0.800

-

-

APACHE II

1.012 (0.990–1.034)

0.295

-

-

  1. Abbreviations: APACHE II, Acute Physiologic Assessment and Chronic Health Evaluation II; CCI, Charlton morbidity index; CKD, chronic kidney disease; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; SOFA Sepsis-related Organ Failure Assessment
  2. Bold values are statistically significant with the value < 0.05