Fig. 1

Celastrol treatment decreased the urinary protein in renal tissue of IgAN rats. The 24-hour urinary protein quantification (A), serum ALT (B), serum albumin (C) and serum urea nitrogen (D) levels in the IgAN rats. C, control group; M, model group; CL-H, celastrol high dose group; CL-L, celastrol low dose group; MP, methylprednisolone group. Data are expressed as the means ± SD. ***p < 0.001 vs. the control group; ###p < 0.001, ##p < 0.01 vs. the model group