Parameter | Sensitivities | Specificities | AUC (95% CI) | P | Youden index |
---|---|---|---|---|---|
Disease severity scores | Â | Â | Â | Â | Â |
APACHE II score | 0.825 | 0.471 | 0.628 (0.532–0.724) | 0.012 | 0.296 |
Sequential organ failure assessment (SOFA) score | 0.333 | 0.922 | 0.612 (0.504–0.720) | 0.031 | 0.255 |
Renal parameters | Â | Â | Â | Â | Â |
Renal resistive index | 0.93 | 0.353 | 0.667 (0.565–0.769) | 0.004 | 0.283 |
Mean arterial pressure (mmHg) | 0.333 | 0.882 | 0.606 (0.504–0.708) | 0.045 | 0.215 |
Urine output (mL/day) | 0.789 | 0.431 | 0.606 (0.512–0.700) | 0.041 | 0.220 |
Serum creatinine (mg/dL) | 0.789 | 0.392 | 0.611 (0.510–0.712) | 0.036 | 0.181 |
Inflammatory markers | Â | Â | Â | Â | Â |
C-reactive protein (mg/L) | 0.649 | 0.647 | 0.663 (0.562–0.764) | 0.009 | 0.296 |
Procalcitonin (ng/mL) | 0.526 | 0.745 | 0.625 (0.521–0.729) | 0.024 | 0.271 |
Coagulation parameters | Â | Â | Â | Â | Â |
D-dimer (µg/mL) | 0.772 | 0.510 | 0.632 (0.531–0.733) | 0.018 | 0.282 |
Platelet count (x10^3/µL) | 0.579 | 0.706 | 0.666 (0.567–0.765) | 0.008 | 0.285 |
Prothrombin time (seconds) | 0.614 | 0.686 | 0.669 (0.571–0.767) | 0.007 | 0.300 |
Fibrinogen (g/L) | 0.544 | 0.745 | 0.637 (0.534–0.740) | 0.020 | 0.289 |
INR | 0.842 | 0.451 | 0.638 (0.538–0.738) | 0.019 | 0.293 |