The predictive value of renal vascular resistance index and serum biomarkers for sepsis-associated acute kidney injury: a retrospective study

Table 5 The predictive value of renal vascular resistance index and serum biomarkers for sepsis-associated AKI

Parameter	Sensitivities	Specificities	AUC (95% CI)	P	Youden index
Disease severity scores
APACHE II score	0.825	0.471	0.628 (0.532–0.724)	0.012	0.296
Sequential organ failure assessment (SOFA) score	0.333	0.922	0.612 (0.504–0.720)	0.031	0.255
Renal parameters
Renal resistive index	0.93	0.353	0.667 (0.565–0.769)	0.004	0.283
Mean arterial pressure (mmHg)	0.333	0.882	0.606 (0.504–0.708)	0.045	0.215
Urine output (mL/day)	0.789	0.431	0.606 (0.512–0.700)	0.041	0.220
Serum creatinine (mg/dL)	0.789	0.392	0.611 (0.510–0.712)	0.036	0.181
Inflammatory markers
C-reactive protein (mg/L)	0.649	0.647	0.663 (0.562–0.764)	0.009	0.296
Procalcitonin (ng/mL)	0.526	0.745	0.625 (0.521–0.729)	0.024	0.271
Coagulation parameters
D-dimer (µg/mL)	0.772	0.510	0.632 (0.531–0.733)	0.018	0.282
Platelet count (x10^3/µL)	0.579	0.706	0.666 (0.567–0.765)	0.008	0.285
Prothrombin time (seconds)	0.614	0.686	0.669 (0.571–0.767)	0.007	0.300
Fibrinogen (g/L)	0.544	0.745	0.637 (0.534–0.740)	0.020	0.289
INR	0.842	0.451	0.638 (0.538–0.738)	0.019	0.293

ISSN: 1471-2369