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Table 1 Baseline characteristics of patients

From: Sodium zirconium cyclosilicate versus sodium polystyrene sulfonate for treatment of hyperkalemia in hemodialysis patients: a randomized clinical trial

 

SZC group (n = 60)

SPS group (n = 60)

P

Age (years)

47.4 ± 10.4

51.6 ± 13.0

0.083

Sex

   

 Male

33 (55%)

31 (51.6%)

0.841

 Female

27 (45%)

29 (48.3%)

BMI (kg/m2)

27 ± 4.5

27.8 ± 5.9

0.449

Duration of HD (years)

7 ± 4.6

6.6 ± 6.1

0.412

Cause of ESRD

   

 Hypertension

21 (35%)

27 (45%)

 

 DM

12 (20%)

15 (25%)

 

 Chronic pyelonephritis

6 (10%)

3 (5%)

 

 Glomerulonephritis (GN)

8 (13.3%)

5 (8.3%)

 

 ADPCKD

6 (10%)

4 (6.6%)

 

 Others

7 (11.6%)

6 (10%)

 

Potassium raising medications

   

 ACEIs/ARBs use

5 (8.3%)

5 (8.3%)

1.000

 MRAs use

1 (1.6%)

1 (1.6%)

1.000

Vascular access

   

 AVF

48 (80%)

54 (90%)

0.102

 Catheter

12 (20%)

6 (10%)

HD prescription

   

 Blood flow rate (ml/min) (QB)

318.2 ± 41.0

307.2 ± 34.1

0.146

 Dialysate flow (ml/hr) (QD)

594.4 ± 103.5

577.2 ± 94.8

0.391

 UF volume (L/session)

3.7 (2.5 − 4.7)

3.25 (3 − 4)

0.147

Presence of residual UOP

   

 Yes

35 (58.3%)

33 (55%)

0.732

 No

25 (41.7%)

27 (45%)

Total cholesterol (mg/dl)

179.4 ± 25.8

182.2 ± 36.0

0.656

Serum triglycerides (mg/dl)

131 (107–178)

133.5 (115–150)

0.603

Hemoglobin (g/dl)

9.6 ± 1.8

9.6 ± 1.7

0.857

Albumin (g/dl)

3.85 ± 0.3

3.76 ± 0.4

0.218

Serum electrolytes

   

 Calcium (mg/dl)

8.9 ± 1.1

9.28 ± 0.9

0.078

 Phosphorus (mg/dl)

5.8 (4.9–7)

6 (5.3–6.6)

0.779

 Sodium (mEq/L)

136.1 ± 15.8

136.1 ± 3.8

0.993

 Potassium (mEq/L)

5.6 ± 0.2

5.6 ± 0.3

0.892

Serum PTH (pg/ml)

301 (132.6–494)

456 (179–822.5)

0.180

CRP (mg/l)

5.5 (4–13)

4.9 (3.2–9.1)

0.273

Kt/V

1.42 ± 0.3

1.40 ± 0.2

0.690

URR

69.7 ± 9.6

69.5 ± 8.6

0.926

  1. p: p value for comparing between the two groups
  2. Normally quantitative data were expressed as Mean ± standard deviation (SD) while non-normally quantitative data were expressed as Median with interquartile ranges (IQR), or absolute numbers as appropriate
  3. ACEIs: angiotensin converting enzyme inhibitors, ADPCKD: autosomal dominant polycystic kidney disease, ARBs: angiotensin receptor blockers, AVF: arteriovenous fistula, BMI: body mass index, CRP: C reactive protein, DM: diabetes mellitus, ESRD: end stage renal disease, HD: hemodialysis, Kt/V: measuring dialysis adequacy, MRAs: mineralocorticoid antagonists, PTH: parathyroid hormone, UF: ultrafiltration, UOP: urine output, URR: urea reduction ratio