Fig. 3
From: CIAPIN1 attenuates ferroptosis via regulating PI3K/AKT pathway in LPS-induced podocytes
CIAPIN1 overexpression activates phosphoinositide 3-kinase (PI3K)/ protein kinase B (Akt) pathway in LPS-treated podocytes. (A) Representative gel blots depicting levels of phosphorylated PI3K (p-PI3K, p85, Tyr458) and phosphorylated Akt (p-Akt, Ser473). (B, C) Quantification analysis of p-PI3K (normalized to total PI3K) and p-Akt (normalized to total Akt). Data represent the average of three independent experiments (mean ± SD). ***P < 0.001 vs. control group; ###P < 0.001 vs. LPS + Vector group