Table 3 Pregnancy descriptions and outcomes. Pregnancy outcomes of the cohort and characteristics of delivered infants. P + C3G consists of pregnancies occurring before C3G presentation, while C3G + P consists of those occurring during or after C3G presentation
From: Pregnancy outcomes in C3 glomerulopathy: a retrospective review
Outcomes | n = 79 pregnancies and 61 deliveries (%) [SD] | ||
|---|---|---|---|
Timing of Diagnostic Biopsy | |||
Before Pregnancy | 47 (59%) | ||
During Pregnancy | 0 (0%) | ||
After Pregnancy | 32 (41%) | ||
Mother’s Onset of C3G Symptoms | |||
Before Pregnancy | 32 (41%) | ||
During Pregnancy | 5 (6%) | ||
After Pregnancy | 42 (52%) |
Full Cohort n = 79 pregnancies and 61 deliveries | P + C3G n = 42 pregnancies and 34 deliveries | C3G + P n = 37 pregnancies and 27 deliveries | |
|---|---|---|---|
Gestation | |||
Mean Gestational Age | 37w 6d (± 2w 4d) | 38w 5d (± 2w 0d) | 36w 4d (± 2w 6d) |
Median Gestational Age | 39w 0d | 40w 0d | 37w 0d |
Prematurity (< 37 weeks) | 17 (28%) | 4 (12%) | 12 (44%) |
Birth Weight | |||
Mean Birth Weight | 6 lb. 11 oz (± 1 lb. 10 oz) | 7 lb. 6 oz (± 1 lb. 5 oz) | 5 lb. 14 oz (± 1 lb. 7 oz) |
Median Birth Weight | 6 lb. 13 oz | 7 lb. 7 oz | 6 lb. 1 oz |
Low Birth Weight (< 5.5 lbs.) | 12 (20%) | 1 (3%) | 11 (41%) |
Pregnancy Loss | 18 (23%) | 8 (19%) | 10 (27%) |
Spontaneous Miscarriage | 13 (72%) | 8 (100%) | 5 (50%) |
Elective Abortion | 3 (17%) | 0 (0%) | 3 (30%) |
Ectopic Pregnancy | 1 (6%) | 0 (0%) | 1 (10%) |
Stillbirth | 1 (6%) | 0 (0%) | 1 (10%) |
Cesarean Section | 18 (30%) | 6 (18%) | 12 (44%) |
Preeclampsia | 20 (33%) | 4 (12%) | 16 (59%) |
Eclampsia | 1 (2%) | 0 (0%) | 1 (4%) |
HELLP Syndrome | 0 (0%) | 0 (0%) | 0 (0%) |
Maternal Death | 0 (0%) | 0 (0%) | 0 (0%) |
Neonatal Health Issues | 5 (8%) | 0 (0%) | 5 (19%) |
Neonatal Death | 0 (0%) | 0 (0%) | 0 (0%) |
Gravidity | |||
Primiparous | 32 (41%) | 15 (36%) | 17 (46%) |
Multiparous | 47 (59%) | 27 (64%) | 20 (54%) |