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Table 2 General characteristics of hemodialyzed (A - before, B - after HD), peritoneal dialysis (PD) treated Conservative (PNN) patients before and after kidney transplantation (TEA and TE B) and control group (NK) participating in the study (mean ± OS)

From: Renalase, dopamine, and norepinephrine as markers for the development of hypertension in CKD patients

Parameters

HD A

HD B

PD

CKD

TE A

TE B

NK

P*

P**

Kt/V

1,34 ± 0,2

1,34 ± 0,2

2,94 ± 0,7

-

-

-

-

NS

NS

Concentration of creatinine [mg/dl

6,5 ± 2,6

3,14 ± 0,2

4,78 ± 2,3

2,64 ± 1,05

6,36 ± 2,5

2,1 ± 2,37

0,82 ± 0,18

< 0,001

< 0,001

GFR

[ml/min./1,73m2]

12 ± 11

24 ± 11

20 ± 11

37 ± 25

11 ± 9

71 ± 44

116 ± 24

< 0,001

< 0,001

Concentration of uric acid [mg/dl]

5 ± 2,38

3,49 ± 1,2

5,69 ± 1,03

6,29 ± 1,24

5,5 ± 1,1

5,55 ± 1,95

6,34 ± 1,07

< 0,001

< 0,001

Concentration of albumin [g/dl]

5,65 ± 2,4

3,56 ± 0,78

5,67 ± 4,2

3,66 ± 0,84

3,7 ± 0,6

3,15 ± 1,95

5,75 ± 0,7

0,0006

0,0131

Concentration of phosphorus

[mg/dl]

1,52 ± 0,44

1,8 ± 0,58

1,55 ± 0,3

1,31 ± 0,3

1,23 ± 0,38

1,81 ± 0,51

NS

CRP [mg/L]

0,9 ± 0,4

1,1 ± 0,6

1,4 ± 0,6

0,7 ± 0,5

2,3 ± 1,2

25 ± 4,0

0,3 ± 0,1

0,01

0,01

Systolic BP, [mmHg]

142 ± 12

134 ± 7

145 ± 20

142 ± 10

137 ± 9

119 ± 4

115 ± 8

NS

NS

Diastolic BP, [mmHg]

87 BP ± 5

78 ± 5

90 ± 5

80 ± 6

83 ± 7

75 ± 5

72 ± 4

NS

NS

BMI

[BMI index]

25,9 ± 3,9

27,2 ± 2,1

31 ± 2,9

26,3 ± 3,8

-

25,1 ± 3,6

NS

NS

Diabetes

N – 24

Y – 8

N – 25

Y – 6

N – 20

Y – 10

N – 23

Y – 1

-

N – 31

Y – 0

0,01

NS

Dyslipidemia

N – 26

Y – 6

N – 25

Y – 6

N – 14

Y – 16

N – 8

Y – 16

-

N – 31

Y – 0

0,01

NS

Hypertension

N – 7

Y – 25

N – 13

Y – 18

N – 15

Y – 15

N – 3

Y – 21

-

N – 31

Y – 0

NS

NS

  1. P* - statistical significance for differences between HD, PD, CKD, TE, and NK groups for quantitative variables - Kruskal Wallis rank ANOVA and Fisher’s exact test for qualitative variables;
  2. P** - statistical significance for differences between HD, PD CKD, and TE groups for quantitative variables -
  3. Y-Yes; N-No
  4. BMI-Body mass index is the ratio of weight to height, expressed in one value - the BMI index
  5. Dyslipidemia- The diagnosis was confirmed by testing lipid parameters if one or more abnormalities were present, such as blood cholesterol level > 5.2 mmol/l (200 mg/dl); triglycerides > 1.7 mmol/l (150 mg/dl); LDL cholesterol > 2.58 mmol/l (100 mg/dl) and/or HDL cholesterol < 1.03 nmol/l (40 mmol/l)
  6. GFR -glomerular filtration rate- Cl = U × V/P
  7. Cl – clearance of the tested substance (ml/min), U – concentration of the substance in urine (mg/dl or mmol/l), V – urine volume (ml/min), P – concentration of the substance in serum (mg/dl or mmol/l)