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Table 2 Characteristics of included quantitative and mixed-methods studies (n = 8)

From: Patients’ transition experience and care from predialysis to dialysis: a theory-guided integrative review

Author

(year)

Country

Study design

Participants

Key findings

Framework alignment

Extended themes

Ma

(2010)

China

Non-RCT

150 PD-eligible patients

Predialysis education improved adherence (82.1% vs. 41.7%, P < 0.001) and work capacity recovery (68.0% vs. 38.9%, P < 0.001).

- Response patterns: Process (adherence); Outcome (work capacity recovery)

- Intervention strategies

Cho

(2012)

South Korea

Retrospective cohort

1218 advanced CKD patients

Multidisciplinary predialysis education reduced unplanned dialysis (8.7% vs. 24.2%, P < 0.001), hospital days (2.16 vs. 5.05 days/year, P = 0.024), and cardiovascular events (2.7% vs. 9.4%, HR = 0.24, P = 0.017).

- Response patterns: Outcome (unplanned dialysis, hospitalization, complications)

- Intervention strategies

Fishbane

(2017)

USA

RCT

130 advanced CKD patients

Home visits reduced hospitalization rates (0.61 vs. 0.92, RR = 0.66, P = 0.04).

- Response patterns: Outcome (hospitalization)

- Intervention strategies

Schanz

(2017)

Germany

Retrospective cohort

336 new dialysis patients

In-hospital education increased free dialysis choice (28.5–62.7%, P < 0.0001) and PD utilization (16.6–27.6%, P = 0.02).

- Response patterns: Outcome (autonomous decision-making)

- Intervention strategies

Shi

(2019)

China

Retrospective cohort

233 advanced CKD patients

Hierarchical management reduced RRT use (39.6% vs. 53.5%, P = 0.037) and temporary catheterization (77.4% vs. 96.7%, P = 0.003).

- Response patterns: Outcome (unplanned dialysis)

- Intervention strategies

Kaiser

(2020)

Israel

Prospective cohort

98 advanced CKD patients

Virtual CKD care improved knowledge levels (52.0–94.0%, P < 0.001) and home dialysis interest (36.0–68.0%, P = 0.047).

- Response patterns: Process (health literacy)

- Intervention strategies

Cervantes

(2021)

USA

Mixed-

methods

26 undocumented patients transitioning from emergency to scheduled HD

1. Anxiety and burden: Navigating care changes.

2. Outcomes: Restored hope and humanity.

3. Health gains: Quality-of-life improvements (P < 0.001) and symptom relief (P < 0.05).

- Transition nature: Change (negative emotions)

- Transition conditions: Personal (negative psychology); Community (occupation); Society (stigma, insurance)

- Response patterns: Process (rebuilding confidence, restoring dignity); Outcome (hope restoration, improvement in quality of life)

Transition conditions:

Dialysis-related (symptoms)

Hundemer

(2023)

Canada

Retrospective cohort

1070 advanced CKD patients

Social determinants (education: OR = 1.71, 95% CI = 1.09–2.69; employment: OR = 1.85, 95% CI = 1.18–2.92; marital status: OR = 1.44, 95% CI = 1.07–1.93) influenced transition to kidney failure.

Transition conditions: Community (occupation)

Transition conditions:

Interpersonal (healthcare support)