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Table 3 Predictors of progression of chronic kidney disease in patients who underwent renal artery revascularization

From: Predictors of kidney disease progression after renal artery stenting

 

Unadjusted

Multivariate Cox model*

HR

95% CI

p

HR

95% CI

p

Age

1.01

0.97–1.06

0.569

0.99

0.90–1.01

0.590

Male sex

0.75

0.31–1.85

0.538

0.74

0.22–2.43

0.616

Diabetes mellitus

2.22

0.93–5.31

0.073

2.33

0.9–6.03

0.079

Serum creatinine

1.90

1.31–2.76

< 0.001

1.63

1.02–2.61

0.04

Systolic BP

1.01

0.99–1.02

0.292

-

-

-

Diastolic BP

1.01

0.98–1.04

0.523

-

-

-

Pulse pressure

1.01

0.99–1.04

0.310

   

Triglyceride

0.99

0.99–1.01

0.128

   

LDL-cholesterol

0.99

0.98-1.00

0.152

   

C-reactive protein

1.01

0.99–1.03

0.265

   

Peak systolic velocity per 10 cm/sec increase

1.04

0.99–1.09

0.099

1.05

1.001–1.010

0.017

Resistivity index (per 0.1 increase)

4.08

0.04–471

0.126

-

-

-

Carbon dioxide vs. contrast agent

0.67

0.19–2.43

0.546

-

-

-

Improvement in kidney function

0.31

0.07–1.33

0.115

-

-

-

AKI after the procedure

7.76

1.93–31.1

0.004

10.18

2.3–45.4

0.002

Stage 1 AKI vs. no AKI

0.05

0.01–3178

0.739

   

Stage 2–3 AKI vs. no AKI

27.9

6.1-128.6

< 0.001

   

Restenosis

0.67

0.22–2.04

0.482

-

-

-

  1. The model included age, sex, and variables that had a significant association with the progression of chronic kidney disease in unadjusted analysis (serum creatinine before the procedure, diabetes mellitus, peak systolic velocity on renal Doppler ultrasound, and acute kidney injury after the stent placement). Independent predictors of progression remained the same factors when the multivariate model included stage 2–3 AKI instead of AKI
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BMC Nephrology

ISSN: 1471-2369

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