Table 2 Dynamic changes in immune function in children with SDNS/FRNS treated with RTX

B cells [M(P₂₅ ~ P₇₅)]/ (cells/ul)

364(320~669)^a

1(0.6 ~ 5.0)^b

0(0 ~ 0)^c

0(0 ~ 0)^c

0(0 ~ 0)^c

76(7.25~107)^d

300(253~364)^a

-

< 0.001

CD3 T-cells [M(P₂₅ ~ P₇₅)]/ (cells/ul)

2323(1256~3146)^a

2539(1339~4260) ^a

2591(2237~3381) ^a

2405(1822~3010) ^a

2797(2373~2927) ^a

3226(3036~3226 ^a

2181(1800~2537) ^a

-

0.083

CD4 T-cells [M(P₂₅ ~ P₇₅)]/ (cells/ul)

1124(907~1478) ^ab

1240(448~1478) ^ab

1272(978~1289) ^ab

917(375~1362)^ac

1120(1045 ~ 1154) ^ab

1376(1326~1515)^bd

894(842~1398) ^ab

-

0.214

CD8 T-cells [M(P₂₅ ~ P₇₅)]/ (cells/ul)

1192(533~1767) ^a

1063(920~2071) ^a

1269(933~1602) ^a

1233(1024 ~ 1405) ^a

1397(1131 ~ 1403) ^a

1549(1293~1549) ^a

836(805~1067) ^a

-

0.214

CD4/CD8 [n/m]

0.77(0.67~1.18) ^a

0.83(0.47~1.14) ^a

0.86(0.71~1.17) ^a

0.73(0.53~0.95) ^a

0.84(0.74~0.84) ^a

0.93(0.89~0.97) ^a

1.10(1.01~1.37) ^a

-

0.371

NK cells [M(P₂₅ ~ P₇₅)]/ (cells/ul)

130(104~330) ^a

234(174~351)^ab

337(248~492)^bc

295(234~344)^ab

310(262~314)^ac

397(302~501)^b

381(249~477)^bc

-

0.080

IgG [\(\:\overline{x}\)±s]/(g/L)

5.90 ± 2.96 ^a

6.30 ± 2.79 ^a

7.47 ± 2.49 ^a

-

-

-

-

F=0.61

0.552

IgM [M(P₂₅ ~ P₇₅)]/ (g/L)

1.11(1.01~1.51) ^a

0.98(0.85~1.26) ^b

0.71(0.48~0.75) ^c

-

-

-

-

-

0.012

IgA [M(P₂₅ ~ P₇₅)]/ (g/L)

1.20(1.02~1.39) ^a

1.14(0.87~2.51) ^a

1.48(0.78~1.68) ^a

-

-

-

-

-

0.829

C4 [M(P₂₅ ~ P₇₅)]/

0.21(0.14~0.30) ^ab

0.20(0.11~0.23) ^a

0.28(0.20~0.29) ^b

-

-

-

-

-

0.418

C3 [M(P₂₅ ~ P₇₅)]/

1.20(1.09~1.36) ^a

1.13(1.08~1.25) ^ab

1.10(1.03~1.10) ^b

-

-

-

-

-

0.225