Skip to main content

Table 2 Comparison of the IC-MPGN and C3G

From: Clinical characteristics and short term outcomes of childhood immune complex membranoproliferative glomerulonephritis and C3 glomerulopathy: a single centre retrospective study

Parameters

ICMPGN (n = 28)

C3G (n = 07)

P- value

Age (years)

10.3 ± 2.9

11.1 ± 3

0.51

Sex (boys)

17 (61%)

5 (71%)

0.60

Presentation

Acute GN

15(54%)

2 (29%)

0.77

RPGN

02 (7%)

4 (57%)

Nephrotic syndrome

11 (39%)

1 (14%)

Hypertension

20 (71%)

3 (43%)

0.15

eGFR less than 90 ml/min/1.73m2)

11 (39%)

4(57%)

0.43

S. Albumin

2.6 ± 0.75

2.9 ± 0.73

0.31

Low C3 level

20 (71%)

7 (100%)

0.10

Low C4 level

5 (18%)

1 (14%)

0.82

Crescents on biopsy

14 (50%)

4 (57%)

0.73

Outcomes at 18 months

Complete remission

13 (47%)

3 (43%)

0.77

Partial remission

11 (39%)

3 (43%)

No response

2 (7%)

1 (14%)

CKD/ESKD

2 (7%)

0

  1. CKD, Chronic kidney disease; ESKD, End stage kidney disease; IQR, Interquartile
  2. Range; eGFR, Estimated glomerular filtration rate