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Table 3 Antioxidants for the treatment of AKI and the corresponding mechanisms

From: Molecular mechanisms and therapeutic interventions in acute kidney injury: a literature review

Antioxidants

Mechanisms

SkQR1 [34]

Protection of mitochondria

NAC [41]

Reduction of CI-AKI

Vitamin C [43]

Capturing RNS and ROS

Vitamin E [44]

Reducing the incidence of CI-AKI in CKD patients

Lipoic acid [45]

Inhibit oxidative stress and inflammatory response

Coenzyme Q10 [46]

Antiperoxidant, anti-apoptotic, and anti-inflammatory protection

  1. Note: SkQR1:10-(6’-plastoquinonyl) decylrhodamine 19, NAC: N-acetylcysteine, RNS: Reactive nitrogen species, ROS: Reactive oxygen species, AKI: Acute kidney injury, CKD: Chronic kidney disease, CI-AKI: Contrast-associated acute kidney injury