Table 6 Laboratory findings in APSGN and PIGN at presentation: urinary findings, serum complements, serological evidence of Streptococcal infection and ANA status
From: A narrative review of acute post-streptococcal glomerulonephritis in Nepali children
Studies | Number of cases | Urinary findings | Serum Complement level | Serological evidence of strep infection | ANA status |
|---|---|---|---|---|---|
Malla K et al. [3] | 92 | Haematuria: 100% NRP: 16.9% RBC casts: NA Pyuria: 15.2% | C3 level: NA C4 level: NA | Positive ASOT: 50% Positive Anti-DNase B: NA | NA |
Shah GS et al. [4] | 94 | Haematuria: 95.7% NRP: 5.3% RBC casts: 0% Pyuria: 34% | C3 level: NA C4 level: NA | Positive ASOT: 34% Positive Anti-DNase B: NA | NA |
Poudel et al. [35] | 30 | Haematuria: 67% NRP: 6.7% RBC casts: NA | Low C3: 97% C4 level: NA | Positive ASOT: 60% Positive Anti-DNase B: NA | ANA (n = 9) Normal = 9 (100%) |
Shah et al. [27] | 41 | Haematuria: 90.2% NRP: 17% RBC cats: NA Granular casts: 24.3% | Low C3: 85.3% C4 level: NA | Positive ASOT: 65.8% Positive Anti-DNase B: NA | ANA (n = 12) Normal: 11 (91.6%) Positive:1 (8.3%)* |
Yadav et al. [36] | 74 | Haematuria: 94.6% Sub-NRP: 52% RBC casts: NA Pyuria: 16% | Low C3: 100% C4 level: NA | Positive ASOT: NA+ Positive Anti-DNase B: NA | NA |
Adhikari et al. [26] | 48 | Haematuria: 81.2% Proteinuria:62.5% RBC casts: NA | Low C3: 72.9% C4 level: NA | Positive ASOT: 45.8% Positive Anti-DNase B: NA | NA |
Dhakal et al. [28] | 77 | Haematuria: 100% NRP: 27.3% Sub-NRP: 20.8% Pyuria: 35% RBC casts: NA | Low C3: 96.1% Low C4: 7.8% | Positive ASOT: 72.7% Positive Anti-DNase B: 86.9% | ANA (n = 5) Normal = 5 (100%) |
Kalakheti et al. [23] | 46 | Haematuria: 78.2% Proteinuria: 67.3% NRP: 10.9% Pyuria: 37% RBC casts: NA | Low C3: 95.7% C4 level: NA | Positive ASOT: 50% Positive Anti-DNase B: NA | NA |
Shrestha et al. [24] | 63 | Haematuria: 93.6% NRP: 3.1% Sub-NRP: 28.5% Pyuria: 7.9% RBC casts: NA | Low C3: 61.9% C4 level: NA | Positive ASOT: 54% Positive Anti-DNase B: Done in one patient, which was positive | ANA (n = 9) Normal: 8 (88.9%) Positive: 1 (11.1%)# |