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Fig. 7 | BMC Nephrology

Fig. 7

From: Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics

Fig. 7

The expression of hub genes in other datasets. (A-C) The expression profiles of three hub genes are presented across three datasets: IRI-AKI (GSE268009), Cis-AKI (GSE106993), and CI-AKI (GSE130795). (D) Within the LPS-AKI dataset (GSE199598), the expression levels of these three hub genes are shown for the LPS-AKI group, which received a dose of 5 mg/kg of LPS. (E) Following the administration of 10 mg/kg of LPS to mice, the expression of the three hub genes was assessed at various time points (0 h, 18 h, and 42 h). At the 42 h time point, the mice were further categorized into two groups: those with renal function recovery and those with persistent renal injury. (* p < 0.05, ns represents no significance)

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BMC Nephrology

ISSN: 1471-2369

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