Table 1 Comparison of maternal and infant characteristics, delivery room resuscitation, and infant baseline growth parameters by patent ductus arteriosus (PDA) treatment status
Treated PDA (n = 261) | No treatment of PDA (n = 345) | p-value* | |
|---|---|---|---|
Gestational age at birth n (%) | |||
24 Weeks | 87 (33.3) | 56 (16.2) | < 0.0001 |
25 Weeks | 83 (31.8) | 68 (19.7) | |
26 Weeks | 50 (19.2) | 94 (27.2) | |
27 Weeks | 41 (15.7) | 127 (36.8) | |
Female Sex | 125 (47.9) | 173 (50.1) | 0.58 |
Maternal Race | |||
Black/African American n (%) | 49 (18.8) | 85 (24.6) | 0.12 |
Other n (%) | 22 (8.4) | 17 (4.9) | |
Unknown n (%) | 6 (2.3) | 11 (3.2) | |
White n (%) | 184 (70.5) | 232 (67.2) | |
Maternal Ethnicity | |||
Hispanic/Latino | 55 (21.1) | 80 (23.2) | 0.46 |
Not Hispanic/Latino | 201 (77.0) | 262 (75.9) | |
Unknown | 5 (1.9) | 3 (0.9) | |
Multiple gestations (≥ 2 live born infants) n (%) | 77 (29.5) | 81 (23.5) | 0.09 |
Diabetes n (%) | 14 (5.4) | 21 (6.1) | 0.71 |
Hypertension n (%) | 19 (7.3) | 30 (8.7) | 0.53 |
Pre-eclampsia n (%) | 43 (16.5) | 49 (14.2) | 0.44 |
Prenatal steroids, n (%) | |||
None | 19 (7.5) | 25 (7.4) | 0.28 |
1 dose | 59 (23.2) | 61 (18.0) | |
2 doses | 160 (63.0) | 220 (65.1) | |
> 2 doses | 16 (6.3) | 32 (9.5) | |
Delivery room resuscitation | |||
Apgar 1 min, median (IQR) | 4 (2–6) | 4 (2–6) | 0.02 |
Apgar 5 min, median (IQR) | 7 (5–8) | 7 (6–8) | 0.01 |
Infant baseline growth parameters | |||
Small for Gestational Age n (%) | 38 (14.6) | 44 (12.8) | 0.51 |
Birth weight, g, mean (SD) | 772.8 (187.1) | 846.3 (188.2) | < 0.0001 |
Birth length, cm, mean (SD) | 32.1 (3.1) | 33.7 (2.8) | < 0.0001 |
Occipitofrontal circumference, cm, mean (SD) | 22.9 (2.3) | 23.5 (1.7) | 0.0003 |