Table 1 Summary of the agreement between the albumin to creatinine ratio (ACR) and protein to creatinine ratio (PCR) determined by test strip analysis as compared to the quantitative lab test in the cross-sectional cohort
QUANTITATIVE ACR | QUANTITATIVE ACR | QUANTITATIVE ACR | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SEMI-QUANTITATIVE ACR | Categories (mg albumin/g creatinine) | SEMI-QUANTITATIVE PCR | Categories (mg albumin/g creatinine) | Qualitative Protein Concentration | Categories (mg albumin/g creatinine) | ||||||||
Categories (mg albumin/g creatinine) | < 30 | ≥ 30 | Total | Categories (mg protein/g creatinine) | < 30 | ≥ 30 | Total | Categories (mg protein/g creatinine) | < 30 | ≥ 30 | Total | ||
< 30 | 711 | 39 | 750 | < 150 | 740 | 86 | 826 | Negative | 678 | 57 | 735 | ||
≥ 30 | 51 | 139 | 190 | ≥ 150 | 22 | 92 | 114 | Positive | 84 | 121 | 205 | ||
Total | 762 | 178 | 940 | Total | 762 | 178 | 940 | Total | 762 | 178 | 940 | ||
Agreement | 90.4% | Agreement | 88.5% | Agreement | 85.0% | ||||||||
Cohen’s kappa (Weighted) | 0.696 | Cohen’s kappa (Weighted) | 0.566 | Cohen’s kappa (Weighted) | 0.538 | ||||||||
Sensitivity | 78.1% (95%CI: 71.3–83.9%) | Sensitivity | 51.7% (95%CI: 44.1–59.2%) | Sensitivity | 68.0% (95%CI: 60.6 − 74.8% | ||||||||
Specificity | 93.3% (95%CI: 91.3–95.0%) | Specificity | 97.1% (95%CI: 95.7–98.2%) | Specificity | 89.0% (95%CI: 86.5 − 91.1%) | ||||||||
PPV | 73.2% (95%CI: 66.3–79.3%) | PPV | 80.7% (95%CI: 72.2–87.5%) | PPV | 59.0% (95%CI: 52.0 − 65.8%) | ||||||||
NPV | 94.8% (95%CI: 93.0–96.3) | NPV | 89.6% (95%CI: 87.3–91.6%) | NPV | 92.2% (9%CI: 90.1 − 94.1%) | ||||||||
LR+ | 11.7 (95%CI: 8.9–15.4) | LR+ | 17.9 (95%CI: 11.6–27.7) | LR+ | 6.2 (95%CI: 4.9–7.7) | ||||||||
LR- | 0.23 (95%CI: 0.18–0.31) | LR- | 0.50 (95%CI: 0.43–0.58) | LR- | 0.36 (95%CI: 0.29–0.45) | ||||||||
Predictive probability | 0.873 95%CI: 0.836–0.910 | Predictive probability | 0.749 (95%CI: 0.700–0.797) | Predictive probability | 0.785 (95%CI: 0.743–0.828) | ||||||||