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Table 2 Correlations between soluble (pro)renin receptor and markers of kidney function stratified by sex and ethnicity

From: The relationship between kidney function and the soluble (pro)renin receptor in young adults: the African-PREDICT study

 

s(P)RR (ng/ml)

Women N = 601

Men N = 555

Black N = 296

White N = 305

Black N = 278

White N = 277

Dependent variable (s)

    

eGFR (ml/min/1.73m2)

r = -0.299

p < 0.001

r = -0.142

p = 0.013

r = -0.209

p < 0.001

r = -0.239

p < 0.001

uACR (mg/mmol)

r= -0.024

p = 0.68

r= -0.030

p = 0.6

r= -0.044

p = 0.46

r= -0.041

p = 0.49

uA1M (ng/ml)

r = 0.091

p = 0.12

r= 0.071

p = 0.21

r= -0.074

p = 0.21

r = 0.052

p = 0.39

Correlations after applying adjustments for age, WC and triglycerides

eGFR (ml/min/1.73m2)

r = -0.213

p < 0.001

r= -0.055

p = 0.34

r= -0.109

p = 0.072

r= -0.078

p = 0.20

uACR (mg/mmol)

r= -0.038

p = 0.52

r= -0.008

p = 0.89

r= -0.032

p = 0.58

r = 0.013

p = 0.82

uA1M(ng/ml)

r= 0.103

p = 0.09

r = 0.115

p = 0.045

r= -0.076

p = 0.20

r = 0.117

p = 0.054

  1. Bold r-values and p-values indicate statistical significance p < 0.05
  2. Abbreviations: s(P)RR, soluble (pro)renin receptor; eGFR, estimated glomerular filtration rate; uACR, urine albumin-creatinine ratio; uA1M, urine alpha 1-microglobulin; WC, waist circumference; N, number of participants