Table 2 Clinical characteristics of patients according to the TyG index quartiles
Variables | Q1 (n = 134) | Q2 (n = 134) | Q3 (n = 133) | Q4 (n = 135) | P-value |
|---|---|---|---|---|---|
TyG index | 8.28 ± 0.24 | 8.80 ± 0.12 | 9.21 ± 0.14 | 9.94 ± 0.45 | < 0.001 |
Age (years) | 50 ± 15 | 50 ± 15 | 52 ± 14 | 51 ± 12 | 0.447 |
Male (n,%) | 86 (64.18%) | 84 (62.69%) | 75 (56.39%) | 86 (63.7%) | 0.529 |
MN duration (months) | 4 (1, 12) | 5.5 (2, 12) | 5 (1.3, 12) | 4 (1.25, 10) | 0.152 |
BMI (kg/m2) | 24.59 ± 4.06 | 25.63 ± 3.98 | 26.40 ± 3.81 | 26.85 ± 3.44 | < 0.001 |
SBP (mmHg) | 135 ± 19 | 137 ± 17 | 135 ± 17 | 137 ± 21 | 0.675 |
DBP (mmHg) | 83 ± 12 | 83 ± 11 | 84 ± 12 | 87 ± 11 | 0.016 |
Smoking (n, %) | 50 (37.31%) | 44 (32.84%) | 42 (31.58%) | 44 (32.59%) | 0.761 |
Drinking (n, %) | 32 (23.88%) | 33 (24.63%) | 33 (24.81%) | 38 (28.15%) | 0.857 |
Hypertension (n, %) | 65 (48.51%) | 80 (59.70%) | 76 (57.14%) | 83 (61.48%) | 0.144 |
DM (n, %) | 7 (5.22%) | 16 (11.94%) | 21 (15.79%) | 43 (31.85%) | < 0.001 |
CHD (n,%) | 4 (2.99%) | 6 (4.48%) | 3 (2.26%) | 3 (2.22%) | 0.672 |
Stroke (n, %) | 4 (2.99%) | 10 (7.46%) | 10 (7.52%) | 8 (5.93%) | 0.359 |
Hyperlipidemia (n, %) | 80 (59.70%) | 95 (70.90%) | 121 (90.98%) | 134 (99.26%) | < 0.001 |
PLA2R-Ab (RU/mL) | 30.23 (3.45, 83.72) | 23.55 (3.94, 105.16) | 35.38 (3.33, 168.45) | 57.43 (9.55, 168.56) | 0.071 |
HDL-C (mmol/L) | 1.43 ± 0.43 | 1.32 ± 0.39 | 1.20 ± 0.29 | 1.15 ± 0.30 | < 0.001 |
LDL-C (mmol/L) | 3.80 (3.01, 4.93) | 4.27 (3.03, 6.05) | 4.29 (3.28, 5.84) | 3.95 (2.74, 5.54) | 0.051 |
TC (mmol/L) | 6.28 ± 1.72 | 7.18 ± 2.76 | 7.17 ± 2.14 | 8.13 ± 2.56 | < 0.001 |
TG (mmol/L) | 1.17 (0.98, 1.36) | 1.73 (1.52, 1.99) | 2.44 (2.12, 2.78) | 4.14 (3.54, 5.59) | < 0.001 |
FBG (mmol/L) | 4.47 ± 0.65 | 4.88 ± 1.02 | 5.25 ± 0.91 | 5.81 ± 1.49 | < 0.001 |
HbA1c (%) | 5.57 ± 0.65 | 5.65 ± 0.64 | 5.76 ± 0.67 | 6.02 ± 0.92 | < 0.001 |
24 h urine protein (g/d) | 3.86 (2.23, 6.60) | 4.20 (2.48, 6.64) | 5.19 (2.95, 7.98) | 6.92 (3.63, 10.46) | < 0.001 |
Serum ALB (g/L) | 29.35 ± 6.61 | 29.42 ± 6.77 | 30.32 ± 5.84 | 28.85 ± 6.19 | 0.235 |
SUA (µmo/L) | 370.99 ± 86.72 | 375.00 ± 89.47 | 377.67 ± 100.41 | 384.91 ± 87.78 | 0.649 |
BUN (mmol/L) | 5.0 (3.8, 6.3) | 4.6 (3.7, 5.6) | 5.2 (4.1, 6.3) | 5.0 (4.1, 6.5) | 0.071 |
Scr (µmo/L) | 65 (56, 78) | 69 (57, 82) | 69 (57, 84) | 72 (61, 86) | 0.031 |
eGFR (mL/min/1.73 m2) | 107.40 ± 28.68 | 101.77 ± 25.11 | 96.20 ± 26.23 | 97.27 ± 24.34 | 0.002 |
ESR (mm/h) | 25 (12, 33) | 28 (14, 45) | 33 (18, 53) | 38 (19, 57) | < 0.001 |
CRP (mg/dL) | 0.17 (0.13, 0.27) | 0.18 (0.14, 0.34) | 0.21 (0.16, 0.33) | 0.23 (0.16, 0.35) | 0.002 |
WBC (×109/L) | 6.24 ± 1.70 | 6.92 ± 2.00 | 6.71 ± 2.08 | 7.41 ± 2.47 | < 0.001 |
HGB (g/L) | 132.66 ± 18.17 | 135.83 ± 19.51 | 136.25 ± 20.63 | 144.44 ± 19.25 | < 0.001 |