Table 1 The demographics and clinical characteristics of immunocompromised CKD patients after severe infection

Basic Information

 Age(years)

46.36 ± 17.10

44.66 ± 16.47

51.01 ± 18.02

0.006

 Gender(Male, n, %)

161(59.2%)

120(60.3%)

41(56.2%)

0.538

 Diabetes(n, %)

57(21.0%)

44(22.1%)

13(17.8%)

0.440

 Hypertension(n, %)

75(27.6%)

52(26.1%)

23(31.5%)

0.379

 CKD1(n, %)

91(33.5%)

66(33.2%)

25(34.2%)

0.867

 CKD2(n, %)

44(16.2%)

35(17.6%)

9(12.3%)

0.297

 CKD3(n, %)

92(33.8%)

65(32.7%)

27(37.0%)

0.504

 CKD4(n, %)

29(10.7%)

21(10.6%)

8(11.0%)

0.923

 CKD5(n, %)

16(5.9%)

12(6.0%)

4(5.5%)

0.864

Laboratory Parameters

 WBC (*10⁹)

9.1(5.57–13.44)

9.3(5.47–13.94)

8.7(5.83–12.79)

0.483

 NEUT (%)

88.0(80.60-92.85)

87.2(80.5–91.9)

89.4(80.45–93.60)

0.262

 Lym (*10⁹)

0.54(0.25-1.00)

0.59(0.318–1.11)

0.4(0.18–0.90)

0.012

 HGB (g/L)

101 ± 26

101 ± 25

101 ± 29

0.928

 PLT (*10⁹)

152(88–219)

154(91–223)

139(66–201)

0.201

 CRP (mg/L)

158.3 ± 87.9

150.1 ± 87.1

180.7 ± 86.7

0.011

 Alb(g/L)

24.6 ± 6.8

24.7 ± 7.0

24.4 ± 6.3

0.748

 Glb(g/L)

24.0 ± 7.8

24.5 ± 7.6

22.5 ± 8.1

0.062

 PCT(µg/L)

6.05(0.97–37.72)

5.34(0.82–39.27)

7.01(1.53–34.26)

0.227

 IL6(ng/L)

137.60(43.52–445.30)

123.40(41.03–352.70)

243.5(63.51–854.10)

0.005

 FIB (g/L)

4.71(3.58–5.88)

4.83(3.80–6.12)

4.54(3.04–5.20)

0.008

 ALT(U/L)

36(24–67)

33(23–57)

45(24–85)

0.004

 AST(U/L)

37(25–65)

34(22–52)

57(35–89)

0.000

 TBIL(µmol/L)

7.2(3.4–12.9)

6.6(3.3–11.1)

9.6(3.6–41.9)

0.001

 LDH (U/L)

763(449–1270)

717(432–1033)

1112(622–2036)

0.000

 proBNP(pmol/L)

784(159–2733)

749(100–2174)

1901(421–3970)

0.003

 CD4 (cells/µl)

139(70–313)

160(93–351)

76(28–213)

0.000

 CD8 (cells/µl)

140(62–262)

157(80–310)

80(35–179)

0.000

 PL(n, %)

76(27.9%)

19(9.5%)

57(78.1%)

0.000

Organ Support

 CRRT(n, %)

150(55.1%)

86(43.2%)

64(87.7%)

0.000

 Vasoactive Drugs (n, %)

93(34.2%)

32(16.1%)

61(83.6%)

0.000

 Ventilation(n, %)

108(39.7%)

45(22.6%)

63(86.3%)

0.000

Infection Status

 BloodInfect(n, %)

172(63.2%)

132(66.3%)

40(54.8%)

0.080

 LungInfect(n, %)

145(53.3%)

89(44.7%)

56(76.7%)

0.000

 OtherInfect(n, %)

39(14.3%)

33(16.6%)

6(8.2%)

0.081

 G⁺ (n, %)

50(18.4%)

39(19.6%)

11(15.1%)

0.393

 G⁻ (n, %)

150(55.1%)

106(53.3%)

44(60.3%)

0.303

 Fungal (n, %)

110(40.4%)

69(34.7%)

41(56.2%)

0.001

 Virus(n, %)

63(23.2%)

37(18.6%)

26(35.6%)

0.003

Disease severity score

 GCS

14(8–15)

14(14–15)

6(6–10)

0.000

 SOFA

8 ± 5

6 ± 4

13 ± 4

0.000

 qPBS

3 ± 3

2 ± 2

6 ± 3

0.000