Skip to main content

Table 4 Univariable and multivariable Cox proportional hazard analyses for the prediction of ESRD in diabetic nephropathy

From: Associations between depressive and anxiety symptoms and incident kidney failure in patients with diabetic nephropathy

Variables

Univariate HR (95% CI)

p value

Multivariable HR (95% CI)

p value

Age

0.990 (0.971, 1.010)

0.330

0.979 (0.957, 1.001)

0.062

Female

0.954 (0.595, 1.527)

0.843

0.937 (0.570, 1.543)

0.799

Hypertension

1.536 (0.851, 2.773)

0.154

0.973 (0.524, 1.807)

0.931

eGFR

0.973 (0.964, 0.982)

< 0.001

0.979 (0.968, 0.991)

< 0.001

Proteinuria

1.087 (1.052, 1.124)

< 0.001

1.074 (1.031, 1.118)

< 0.001

Glycosylated hemoglobin

0.865 (0.755, 0.991)

0.036

0.956 (0.827, 1.105)

0.539

HEI score > 8

3.599 (2.196, 5.896 )

< 0.001

1.825 (1.050, 3.172)

0.033

Pathology characteristics

   

Glomerular class

1.941 (1.481, 2.545)

< 0.001

1.224 (0.868, 1.727)

0.249

IFTA

1.630 (1.222, 2.174)

0.001

1.053 (0.694, 1.597)

0.810

Interstitial inflammation

2.054 (1.373, 3.071)

< 0.001

1.411 (0.925, 2.153)

0.110

Arteriosclerosis

1.327 (0.925, 1.904)

0.124

0.960 (0.626, 1.474)

0.853

  1. Multivariable model was adjusted for age, sex, eGFR, proteinuria, serum albumin, hemoglobin, and all pathological parameters. HR hazard ratio, eGFR estimated glomerular filtration rate, HEI Huaxi Emotional-distress Index, IFTA interstitial fibrosis and tubular atrophy