High-risk Subgroup | Number of participants | Number of events | HR(95%CI) | β coefficient | P value | P for interaction |
---|---|---|---|---|---|---|
Gender | 0.055 | |||||
 Male | 103 | 24 | 0.99(0.97–1.00) | −0.01 | 0.070 |  |
 Female | 114 | 21 | 0.97(0.943–0.988) | −0.04 | 0.003 |  |
Age, yrs | 0.046 | |||||
 < 40 | 99 | 15 | 0.93(0.89–0.97) | −0.07 | < 0.001 |  |
 40–60 | 70 | 17 | 0.98(0.966–0.999) | −0.02 | 0.039 |  |
 ≥ 60 | 46 | 13 | 0.98(0.950–1.006) | −0.03 | 0.113 |  |
Alcohol drinkers | 0.203 | |||||
 Never | 127 | 23 | 0.97(0.954–0.991) | −0.03 | 0.004 |  |
 Current or ever | 98 | 22 | 0.99(0.965–9.992) | −0.02 | 0.041 |  |
Cigarette smokers | 0.251 | |||||
 Never | 194 | 36 | 0.98(0.968–0.991) | −0.02 |  < 0.001 |  |
 Current or ever | 31 | 9 | 0.99(0.994–1.015) | −0.01 | 0.595 |  |
Alcohol use disorders | 0.315 | |||||
 Yes | 21 | 8 | 0.92(0.758–1.126) | −0.08 | 0.434 |  |
 No | 204 | 37 | 0.99(0.974–0.995) | −0.02 | 0.006 |  |
Hypertension | 0.882 | |||||
 Yes | 67 | 14 | 1.04(0.999–1.092) |  + 0.04 | 0.057 |  |
 No | 158 | 31 | 0.97(0.955–0.982) | −0.03 | < 0.001 |  |
Diabetes mellitus | 0.921 | |||||
 Yes | 52 | 12 | 0.99(0.964–1.017) | −0.01 | 0.469 |  |
 No | 173 | 33 | 0.98(0.969–0.993) | −0.02 | < 0.001 |  |
Malaria | 0.175 | |||||
 Yes | 24 | 7 | 0.92(0.112–7.589) | −0.08 | 0.939 |  |
 No | 187 | 38 | 0.98(0.967–0.990) | −0.02 | < 0.001 |  |
HIV | 0.021 | |||||
 Yes | 53 | 19 | 0.94(0.905–0.974) | −0.06 | < 0.001 |  |
 No | 171 | 26 | 0.99(0.979–1.002) | −0.01 | 0.098 |  |
Anemia | 0.705 | |||||
 Yes | 104 | 31 | 0.98(0.921–0.994) | −0.02 | 0.004 |  |
 No | 121 | 14 | 0.98(0.946–1.017) | −0.02 | 0.292 |  |
Blood transfusion | 0.167 | |||||
 Yes | 37 | 9 | 0.88(0.225–3.416) | −0.132 | 0.849 |  |
 No | 177 | 36 | 0.98(0.967–0.991) | −0.02 | < 0.001 |  |