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Table 1 Demographic and clinical characteristics of study participants

From: Impact of estimated glomerular filtration rate (eGFR) on in-hospital mortality: an age- and HIV status-specific retrospective cohort study in Uganda

Variables on admission

Stratified eGFR/ML/min/1.73 m2 subgroups

Q1 = [< 66.8]

56 (24.8)

Q2 = [66.8–99.0]

60(26.5)

Q3 = [99.0–120]

55 (24.3)

Q4 = [≥ 120]

55 (24.3)

P

values

Demographics

Overall = 226

     

Age, yrs [Median(IQR)]

43.0(25.3)

53.0(28.0)

50.5(31.0)

39.0(20.0)

32.0(17.0)

< 0.001

Gender, n(%)

0.440

 Male

103 (45.6)

28 (27.2)

22 (21.4)

26 (25.2)

27 (26.2)

 

 Female

123 (54.4)

28 (22.8)

38 (30.9)

29 (23.6)

28 (22.8)

 

Smoking, n (%)

31 (13.7)

10 (32.3)

10 (32.3)

4 (12.9)

7 (22.6)

0.358

Alcohol, n (%)

98 (43.4)

27 (27.6)

25 (25.5)

22 (22.4)

24 (24.5)

0.835

Clinical characteristics

Mortality, n (%)

45 (19.9)

21 (46.7)

14(31.1)

4(8.9)

6(13.3)

< 0.001

Hospital stays, days

4.0(5.0)

6.07 ± 6.64

4.98 ± 4.00

5.56 ± 5.65

6.42 ± 7.47

0.588

Comorbidities

 Anemia, n(%)

105(46.5)

30(28.6)

27(25.7)

26(24.8)

22(21.0)

0.546

vAlcohol use disorders, n(%)

21(9.3)

4(19.0)

3(14.3)

6(28.6)

8(38.1)

0.309

 Septicemia, n(%)

40(17.7)

16(40.0)

7(17.5)

9(22.5)

8(20.0)

0.090

 Hypertension, n(%)

67(29.6)

30(44.8)

23(34.3)

13(19.4)

1(1.5)

< 0.001

 Pneumonia, n(%)

28(12.4)

5(17.9)

9(32.1)

8(28.6)

6(21.4)

0.719

 DM, n(%)

52(23.0)

26(50.0)

16(30.8)

6(11.5)

4(7.7)

< 0.001

 Malaria, n(%)

39(17.3)

7(17.9)

5(12.8)

11(28.2)

16(41.0)

0.019

 HIV, n(%)

54(23.9)

11(20.4)

14(25.9)

15(27.8)

14(25.9)

0.805

SBP, mmHg [Median(IQR)]

123.0(31.5)

125.0(66.3)

123(43.8)

124.0(24.0)

122.0(23)

0.016

DSP, mmHg [Median(IQR)]

74.0(23.5)

76.0(46.8)

75.0(25.8)

74.0(14.0)

71.0(18.0)

0.022

Laboratories values

 Cr, mg/dl [Median(IQR)]

71.0(37.3)

144.5(316.2)

76.0(21.0)

66.0(16.0)

47(26.0)

< 0.001

 eGFR, min/1.73 m2 [Median(IQR)]

99.0(53.3)

28.5(46.0)

87(16.5)

111.0(8.0)

131(20.0)

< 0.001

 RBS, mmol/L [Median(IQR)]

7.0(2.0)

7.2(4.9)

7.0(3.0)

7.0(2.0)

6.7(1.0)

0.288

 HG, g/dl [Median(IQR)]

11.5(5.3)

10.6(5.6)

11.4(5.4)

11.7(4.7)

12.3(5.3)

0.916

 WBC, 109/L [Median(IQR)]

7.7(7.3)

9.0(9.9)

8.0(7.5)

7.0(7.40)

7.3(4.7)

0.104

Treatment medications

 Diuretics, n(%)

34(15.0)

16(47.1)

10(29.4)

4(11.8)

4(11.8)

< 0.001

 Anti-HTN medic, n(%)

61(27.0)

28(45.9)

20(32.8)

11(18.0)

2(3.3)

< 0.001

 Anti-DM medic, n(%)

52(23.0)

26(50.0)

16(30.8)

6(11.5)

4(7.7)

< 0.001

 Blood transfusion, n(%)

48(21.2)

9(18.8)

14(29.2)

11(22.9)

14(29.2)

0.640

 PPI, n(%)

103(45.6)

20(19.4)

24(23.3)

35(34.0)

24(23.3)

0.016

 Anti-malaria, n(%)

40(17.7)

7(17.5)

6(15.0)

55(24.3)

55(24.3)

0.035

  1. This table highlights the clinical and demographic characteristics of study participants stratified by eGFR, identifying statistically significant variables that should be adjusted for in subsequent analyses to better understand their impact on study outcomes. Data are presented as continuous variables that are not normally distributed, expressed as median (IQR), while non-continuous variables are represented as number (percentage)
  2. The characteristics of the study population (n = 226) are based on hospitalised patient at internal medical department stratified into quartiles(Q) of eGFR
  3. Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, HG Hemoglobin, WBC White blood cells, eGFR Estimated glomerular filtration rate, IQR Interquartile range, RBS Random blood sugar, HTN Hypertension, DM Diabetes mellitus, HIV Human immunodeficiency virus, HIV Human acquired Virus, Hb Hemoglobin, PPI Proton pump inhibitor, RBS Random blood sugar. Bold, statistically significant
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BMC Nephrology

ISSN: 1471-2369

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