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Table 5 Associations of Sarcopenia, SMI, HGS, and depression with osteoporosis by multivariate logistic regression analysis adjusted for age, sex, BMI, dialysis duration, phosphate, calcium, PTH, calcium-phosphorus metabolism drug; triglycerides, HDL-cholesterol, Kt/V

From: Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study

Variables

All

Male

Female

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Sex (male vs. female)

0.864 (0.611, 1.223)

0.410

0.439 (0.271, 0.710)

0.001

        

Age (years)

1.022 (1.007, 1.036)

0.003

1.016 (1.000, 1.031)

0.046

0.999 (0.981, 1.017)

0.918

0.993 (0.974, 1.012)

0.485

1.059 (1.032, 1.087)

< 0.001

1.053 (1.023, 1.083)

< 0.001

BMI (kg/m2)

0.948 (0.902, 0.996)

0.035

0.997 (0.938, 1.060)

0.914

0.942 (0.882, 1.007)

0.077

0.996 (0.915, 1.085)

0.933

0.940 (0.856, 1.022)

0.144

0.982 (0.890, 1.083)

0.714

Dialysis duration (months)

1.007 (1.004, 1.010)

< 0.001

1.007 (1.004, 1.010)

< 0.001

1.007 (1.003, 1.011)

0.001

1.006 (1.002, 1.010)

0.002

1.007 (1.002, 1.012)

0.003

1.008 (1.003, 1.013)

0.003

Sarcopenia

1.919 (1.251, 2.943)

0.003

  

1.859 (1.056, 3.272)

0.032

  

1.901 (0.938, 3.849)

0.075

  

SMI (kg/m2)

  

0.638 (0.494, 0.823)

0.001

  

0.648 (0.499, 0.937)

0.018

  

0.546 (0.339, 0.879)

0.013

Handgrip strength(kg)

  

0.990 (0.964, 1.017)

0.456

  

0.987 (0.958, 1.018)

0.412

  

0.995 (0.937, 1.057)

0.877

Depression

1.452 (1.060, 1.989)

0.020

1.445 (1.050, 1.989)

0.024

1.282(0.852, 1.927)

0.233

1.267 (0.840, 1.910)

0.26

1.886 (1.111, 3.204)

0.019

1.942(1.120, 3.368)

0.018

  1. BMI, body mass index; SMI, skeletal mass index; HDL-cholesterol, high-density lipoprotein cholesterol PTH, parathyroid hormone; Kt/V, fractional clearance index for urea
  2. Adjusted for age, sex, BMI, dialysis duration, phosphate, calcium, PTH, calcium-phosphorus metabolism drug; triglycerides, HDL-cholesterol, Kt/V