Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study

Table 2 The correlation analysis of BMD and factors

Characteristics	Spearman correlation analysis		Multiple stepwise linear regression analysis
Characteristics	r	P value	Unstandardized coefficient	Standardized coefficient	P value
Age (years)	-0.157	< 0.001	-0.001	-0.096	0.010
Female	-0.580	< 0.001	-0.059	-0.305	< 0.001
BMI (kg/m²)	0.218	< 0.001
Dialysis duration (months)	-0.300	< 0.001	-0.0002	-0.154	< 0.001
SMI (kg/m²)	0.570	< 0.001	0.018	0.237	< 0.001
Handgrip strength (kg)	0.483	< 0.001	0.001	0.101	0.021
Gait speed (m/s)	0.102	< 0.001
IPAQ (Met/wk)	-0.016	0.649
MIS	-0.129	< 0.001
CCI	0.068	0.047
Hemoglobin (g/L)	0.026	0.443
Albumin (g/L)	0.056	0.1
CRP (mg/L)	0.036	0.327
Total cholesterol (mmol/L)	-0.149	< 0.001
Triglycerides (mmol/L)	0.054	0.112
HDL-cholesterol (mmol/L)	-0.221	< 0.001	-0.027	-0.079	0.015
LDL-cholesterol (mmol/L)	-0.108	0.002
Phosphate (mmol/L)	0.079	0.022
Calcium (mmol/L)	-0.034	0.319
PTH (pg /mL)	-0.170	< 0.001	-0.00005	-0.162	< 0.001
Vitamin D (nmol/L)	0.001	0.98
Kt/V	-0.357	< 0.001

BMD, bone mineral density; BMI, body mass index; SMI, skeletal mass index; IPAQ, international physical activity questionnaire; Met/wk, metabolic equivalent task minutes per week; MIS, malnutrition inflammation score; CCI, Charlson Comorbidity Index; CRP, C-reactive protein; HDL cholesterol, high-density lipoprotein cholesterol; LDL- cholesterol, low-density lipoprotein cholesterol; PTH, parathyroid hormone; Kt/V, fractional clearance index for urea

ISSN: 1471-2369