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Table 2 Clinical outcomes during follow-up

From: Lifetime progression of IgA nephropathy: a retrospective cohort study with extended long-term follow-up

Variable

All patients (n = 400)

Length of follow-up, n (%)

400 (100)

Median, years (IQR)

16 (9–24)

Use of RAAS inhibitor during follow-up, n (%)

392 (98)

 Yes

272 (69)

 No

120 (31)

Use of corticosteroids during follow-up, n (%)

394 (99)

 Yes

78 (20)

 No

313 (78)

Use of SGLT2 inhibitor during follow-up, n (%)

396 (99)

 Yes

28 (7)

 No

368 (92)

Time-averaged proteinuria (g/24 h), n (%)

341 (85)

 Median (IQR)

1

Proportion of follow-up period with proteinuria < 1 g/24 h, n (%)

341 (85)

 Median, % (IQR)

67 (22–90)

Proportion of measurements with proteinuria < 1 g/24 h, n (%)

341 (85)

 Median, % (IQR)

71 (43–92)

ESKD or death event, n (%)

400 (100)

 Yes

135 (34)

 No

265 (66)

Death event, n (%)

400 (100)

 Yes

69 (17)

 No

331 (83)

Death event without KRT, n (%)

69 (17)

 Yes

34 (49)

 No

35 (51)

ESKD, n (%)

400 (100)

 Yes

101 (25)

 No

299 (75)

KRT, n (%)

400 (100)

 Yes

99 (25)

 No

301 (75)

First event, n (%)

133 (33)

 Death

34 (25.6)

 Dialysis

78 (58.6)

 Transplant

21 (15.8)

Years until first event, n (%)

135 (34)

 Median, years (IQR)

8 (5–14)

Age at first event, n (%)

135 (34)

 Median, years (IQR)

57 (40–68)

Survival rate (have not reached death or KRT), estimate (95% CI), n (%)

400 (100)

 5-year

91 (88–93)

 10-year

79 (76–84)

 15-year

73 (69–78)

 20-year

67 (62–72)

 25-year

62 (56–68)

 30-year

55 (49–63)

Quartile survival estimate, years (95% CI), n (%)

400 (100)

 90%

6 (4–7)

 80%

10 (8–14)

 70%

18 (15–23)

 60%

27 (23-NE)

 50%

NE (29-NE)

  1. For quantitative variables, values are expressed as medians (interquartile ranges [IQR]), and for qualitative variables, values are expressed as n (%). RAAS = Renin–angiotensin–aldosterone system. SGLT2 = Sodium glucose cotransporter 2. KRT = Kidney replacement therapy. ESKD End-stage kidney disease. CI Confidence interval. NE Not estimable