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Table 4 Univariate and multivariate cox regression model for mortality

From: Risk factors for the mortality of hemodialysis patients with COVID-19 in northern Hunan province, China

 

Unadjusted Cox analysis

 

Adjusted Cox analysis

 

Variables

P-values

Hazards ratio (95% CI)

P-values

Hazards ratio (95% CI)

Demographics

 Ages (years)

 < 0.001

1.05 (1.02, 1.07)

 < 0.001

1.09 (1.05, 1.14)

 Male gender

0.79

1.08 (0.62, 1.88)

  

Comorbidities

 Catheter at 1st HD

0.18

1.40 (0.86, 2.28)

  

 Diabetes mellitus

0.30

1.30 (0.80, 2.10)

  

 IHD

0.33

1.31 (0.76, 2.24)

  

 Hypertension

0.22

0.71 (0.41, 1.23)

  

 CVA

0.01

1.91 (1.16, 3.16)

  

 COPD

0.90

1.07 (0.39, 2.95)

  

Laboratory Variables

 Hb (g/L)

0.87

1.00 (0.99, 1.01)

  

 WCC (× 10^9/L)

0.69

1.01 (0.95, 1.08)

  

 Neutrophil (× 10^9/L)

0.79

1.01 (0.95, 1.08)

  

 Lymphocytes (× 10^9/L)

0.01

0.41 (0.20, 0.83)

  

 Monocytes (× 10^9/L)

0.03

0.39 (0.16, 0.92)

  

 NWR

0.003

1.02 (1.01, 1.04)

0.004

1.04 (1.01, 1.07)

 LWR

0.62

0.45 (0.02, 10.62)

  

 MWR

0.08

0.00 (0.00, 2.09)

  

 NLR

0.12

10.92(6.60,26.00)

  

 MNR

0.58

1.45 (0.39, 5.32)

  

 MLR

0.35

1.12 (0.89, 1.42)

  

 PMR

0.52

1.00 (1.00, 1.00)

  

 PLR

0.22

1.00 (1.00, 1.00)

  

 PNR

0.35

1.00 (1.00, 1.00)

  

 Albumin (g/L)

0.19

1.00 (1.00, 1.01)

  

 Ferritin (ug/L)

0.29

1.00 (1.00, 1.00)

  

 Total cholesterol (mmol/L)

0.16

0.84 (0.65, 1.07)

  

 HDL (mmol/L)

0.82

1.08 (0.57, 2.04)

  

 LDL (mmol/L)

0.35

0.85 (0.61, 1.19)

  

 Triglycerides (mmol/L)

0.23

0.85 (0.66, 1.10)

  

 CRP (mg/L)

0.81

1.00 (1.00, 1.00)

  

 TnT (pg/ml)

0.05

1.00 (1.00, 1.00)

  

 ESR

0.67

1.00 (0.99, 1.01)

  

 PCT (ng/L)

0.001

1.01 (1.01, 1.02)

 < 0.001

1.02 (1.01, 1.03)

 PLT (× 10^9/L)

0.07

1.00 (0.99, 1.00)

  

 Phosphate (mmol/L)

0.02

0.57 (0.36, 0.90)

  

 Calcium (mmol/L)

0.87

1.08 (0.45, 2.56)

  

 D-dimer (mg/L)

0.001

1.11 (1.05, 1.17)

  

 EF (%)

0.56

0.99 (0.97, 1.02)

  

 BNP

0.008

2.06 (1.21, 3.51)

  

 PTH (pg/ml)

0.30

1.00 (1.00, 1.00)

  

 Creatinine (umol/L)

0.004

1.00 (1.00, 1.00)

  

Clinical course

 Use of respiratory support

0.11

   

 Use of corticosteroid

0.001

0.42 (0.25, 0.71)

0.001

0.24 (0.10, 0.55)

 Use of antiviral

0.21

0.71 (0.42, 1.21)

  

 Use of ACEI or ARB

0.15

0.66 (0.37, 1.16)

  

 Use of anticoagulant

0.17

0.61 (0.30, 1.23)

  

 CT chest

0.17

   
  1. Continuous data are expressed as median (interquartile range) unless otherwise stated
  2. Bold values represent significance at p < 0.05
  3. HD hemodialysis, IHD ischemic heart disease, CVA cerebrovascular accident, COPD chronic obstructive pulmonary disease, Hb hemoglobin, WCC white cell count, NWR Neutrophil-to-white cell ratio, LWR Lymphocyte-to-white cell ratio, MWR Monocyte-to-white cell ratio, NLR Neutrophil-to-Lymphocyte ratio, MNR Monocyte-to-Neutrophil ratio, MLR Monocyte-to-Lymphocyte ratio, PMR blood platelet-to-Lymphocyte ratio, PLR blood platelet-to-Lymphocyte ratio, PNR blood platelet-to-Neutrophil ratio, HDL high-density lipoprotein, LDL low-density lipoprotein, CRP C-reactive protein, TnT troponin T, ESR erythrocyte sedimentation rate, PCT Procalcitonin, PLT blood platelet, EF ejection fraction, BNP brain natriuretic peptide (≥ 35,000 is expressed as”1″ and < 35,000 as “0″), PTH parathyroid hormone, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, ICU intensive care units
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BMC Nephrology

ISSN: 1471-2369

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