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Table 2 Comparison of patients regarding respiratory support need

From: Risk factors for the mortality of hemodialysis patients with COVID-19 in northern Hunan province, China

Variables

All patients

Noninvasive respiratory support (n = 40)

Invasive respiratory support (n = 34)

NO Respiratory support (n = 156)

P-values

Demographics

 Ages a (years)

67.00 (58.0, 72.25)

72.00 (65.00, 75.00)

69.32 ± 11.56

64.50 (54.25, 71.00)

 < 0.001

 Male gender, n (%)

151 (65.65)

29 (72.50)

22 (64.71)

100 (64.10)

0.60

Comorbidities

 Catheter at 1st HD, n (%)

103 (44.78)

19 (47.50)

21 (61.76)

63 (40.38)

0.07

 Diabetes mellitus, n (%)

96 (41.74)

17 (42.50)

17 (50.00)

62 (39.74)

0.54

 IHD, n (%)

41 (17.83)

12 (30.00)

6 (17.65)

23 (14.74)

0.08

 Hypertension, n (%)

180 (78.26)

28 (70.00)

20 (58.82)

132 (84.62)

0.002

 CVA, n (%)

53 (23.04)

10 (25.00)

9 (26.47)

34 (21.79)

0.80

 COPD, n (%)

15 (6.52)

2 (5.00)

0 (0.00)

13 (8.30)

0.48

Laboratory Variables

 Hb a (g/L)

85.00 (70.00, 106.00)

85.08 ± 29.36

95.06 ± 38.61

87.19 ± 21.85

0.44

 WCC (× 10^9/L)

6.40 (4.74, 9.12)

8.36 (6.41, 12.34)

7.53 (5.78, 10.88)

5.71(4.52, 8.28)

 < 0.001

 Neutrophil (× 10^9/L)

5.22 (3.55, 8.10)

7.14 (5.12, 11.08)

5.86 (4.53, 9.73)

4.30 (3.01, 6.67)

 < 0.001

 Lymphocytes a (× 10^9/L)

0.64 (0.41, 0.92)

0.54 ± 0.31

0.61 (0.36, 0.94)

0.69 (0.46, 0.94)

0.008

 Monocytes a (× 10^9/L)

0.50 (0.31, 0.70)

0.54 ± 0.29

0.46 (0.29, 0.61)

0.52 (0.32, 0.70)

0.65

 NWR

0.83 (0.74, 0.92)

0.90 (0.83, 0.94)

0.85 (0.80, 0.94)

0.79 (0.71, 0.89)

 < 0.001

 LWRa

0.10 (0.06, 0.16)

0.05 (0.03, 0.11)

0.10 ± 0.07

0.12 (0.07, 0.18)

 < 0.001

 MWRa

0.07 (0.05, 0.10)

0.06 ± 0.04

0.06 (0.04, 0.08)

0.08 (0.06, 0.11)

 < 0.001

 NLR

7.81 (4.57, 15.34)

17.89 (7.51, 34.23)

10.42 (5.31, 23.79)

6.24 (3.90, 11.45)

 < 0.001

 MNRa

0.09 (0.06, 0.14)

0.07 ± 0.05

0.07 (0.04, 0.11)

0.11 (0.07, 0.16)

 < 0.001

 MLR

0.74 (0.47, 1.25)

0.95 (0.55, 1.89)

0.69 (0.42, 1.40)

0.73 (0.49, 1.06)

0.71

 PMR

337.92 (209.52, 497.58)

331.72 (215.31, 491.74)

284.10(190.53,494.91)

346.92 (208.68, 505.00)

0.69

 PLR

242.91 (153.18, 420.13)

354.37 (195.28, 664.37)

216.99(118.69,449.53)

231.58 (152.77, 361.39)

0.02

 PNRa

30.73 (19.05, 46.30)

25.70 ± 15.44

23.60 ± 13.88

35.64 (24.91, 50.57)

 < 0.001

 Albumina (g/L)

33.60 (30.00, 39.70)

32.39 ± 5.08

30.60 (27.65, 34.78)

34.63 ± 5.75

0.003

 Ferritina (ug/L)

433.10 (157.70, 997.50)

1000.26 ± 837.85

522.00(236.00,1112.80)

371.45 (146.70,801.08)

0.06

 Total cholesterol a (mmol/L)

3.45 ± 1.03

3.57 ± 0.78

3.06 ± 1.01

3.49 ± 1.06

0.14

 HDL a (mmol/L)

0.94 (0.76, 1.17)

1.01 ± 0.39

0.86 (0.77, 1.19)

0.95 (0.76, 1.15)

0.94

 LDL a (mmol/L)

1.80 (1.34, 2.36)

1.86 ± 0.68

1.72 ± 0.60

1.82 (1.31, 2.42)

0.55

 Triglycerides a (mmol/L)

1.47 (1.05, 2.21)

1.49 (1.19, 2.33)

1.55 ± 0.72

1.44 (1.04, 2.18)

0.77

 CRP a (mg/L)

61.92 (17.21, 138.03)

75.51 (32.90, 216.54)

165.01 ± 114.40

41.90 (14.52, 112.35)

 < 0.001

 TnT (pg/ml)

79.25 (36.43, 170.25)

73.33 (22.00, 246.75)

143.00 (60.48, 305.75)

76.25 (36.75, 138.20)

0.04

 ESR a

74.00 (43.75, 96.50)

88.00 (31.50, 102.50)

70.36 ± 32.40

69.71 ± 31.32

0.95

 PCT (ng/L)

1.81 (0.71, 6.25)

2.59 (1.09, 11.12)

8.54 (1.45, 31.40)

1.42 (0.55, 3.45)

 < 0.001

 PLT a (× 10^9/L)

155.50 (110.75, 218.75)

183.78 ± 97.18

146.50 ± 77.77

162.00 (112.00, 215.00)

0.22

 Phosphate a (mmol/L)

1.63 (1.30, 2.25)

1.98 ± 0.69

1.48 (1.30, 2.03)

1.62 (1.24, 2.27)

0.22

 Calcium (mmol/L)

1.93 (1.77, 2.10)

1.92 (1.53, 2.03)

1.93 (1.77, 2.05)

1.48 (0.89, 2.44)

0.30

 D-dimer (mg/L)

1.75 (1.00, 3.77)

2.48 (0.94, 5.26)

2.69 (1.74, 5.79)

1.48 (0.89, 2.44)

0.04

 EF (%)

57.56 (53.00, 65.00)

60.00 (54.00, 66.50)

62.00 (57.25, 66.00)

60.00 (53.00, 65.00)

0.52

 BNP, n (%)

97 (42.17)

19 (47.50)

11 (32.35)

67 (42.95)

0.40

 PTH (pg/ml)

244.20 (145.40, 411.91)

264.16 ± 189.24

203.97(111.24,537.24)

253.34 (147.44, 411.14)

0.78

 Creatinine a (umol/L)

696.80 (494.25, 989.50)

668.40 ± 395.30

620.97 ± 412.70

734.90(568.75,1045.33)

 < 0.001

Clinical course

 Use of hormone, n (%)

100 (43.48)

23 (57.50)

24 (70.59)

53 (33.97)

 < 0.001

 Use of antiviral, n (%)

67 (29.13)

10 (25.00)

12 (35.29)

45 (28.85)

0.62

 Use of ACEI or ARB, n (%)

54 (23.48)

11 (27.50)

3 (8.82)

40 (25.64)

0.09

 Use of anticoagulant, n (%)

38 (16.52)

10 (25.00)

7 (20.59)

21 (13.46)

 

 ICU Stay, n (%)

73 (31.74)

28 (70.00)

28 (82.35)

17 (10.90)

 < 0.001

CT chest

    

 < 0.001

  Grade 1, n (%)

18 (7.83)

2 (5.00)

1 (2.94)

15 (9.62)

 

  Grade 2, n (%)

72 (31.30)

9 (22.50)

8 (23.53)

55 (35.26)

 

  Grade 3, n (%)

82 (35.65)

11 (27.50)

8 (23.53)

63 (40.38)

 

  Grade 4, n (%)

49 (21.30)

14 (35.00)

16 (47.06)

19 (12.18)

 

Mortality, n (%)

66 (28.70)

17 (42.50)

17 (50.00)

32 (20.51)

 < 0.001

  1. Continuous data are expressed as median (interquartile range) unless otherwise stated
  2. Bold values represent significance at p < 0.05
  3. HD hemodialysis, IHD ischemic heart disease, CVA cerebrovascular accident, COPD chronic obstructive pulmonary disease, Hb hemoglobin, WCC white cell count, NWR Neutrophil-to-white cell ratio, LWR Lymphocyte-to-white cell ratio, MWR Monocyte-to-white cell ratio, NLR Neutrophil-to-Lymphocyte ratio, MNR Monocyte-to-Neutrophil ratio, MLR Monocyte-to-Lymphocyte ratio, PMR blood platelet-to-Lymphocyte ratio, PLR blood platelet-to-Lymphocyte ratio, PNR blood platelet-to-Neutrophil ratio, HDL high-density lipoprotein, LDL low-density lipoprotein, CRP C-reactive protein, TnT troponin T, ESR erythrocyte sedimentation rate, PCT Procalcitonin, PLT blood platelet, EF ejection fraction, BNP brain natriuretic peptide (≥ 35,000 is expressed as”1″ and < 35,000 as “0″), PTH parathyroid hormone, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, ICU intensive care units
  4. aMean ± SD