Fig. 1
A Light microscopic findings on kidney biopsy in case 1. (a) Low-power views show diffuse attenuation of the tubular epithelium and scattered infiltration of inflammatory cells (Elastica–Masson trichrome stain). (b) There were no pathological changes in the glomeruli (periodic acid–Schiff stain). (c) Loss of brush borders, coarse vacuolar degeneration (arrows), flattened cytoplasm, cell detachment (arrowheads), and mitoses were observed in tubular epithelial cells (periodic acid–Schiff stain). B Light microscopic findings on kidney biopsy in case 2. (a) Low-power views show diffuse attenuation of the tubular epithelium, scattered infiltration of inflammatory cells, and focal interstitial fibrosis (Elastica–Masson trichrome stain). (b) There were no pathological changes in the glomeruli (periodic acid–Schiff stain). (c) Loss of brush borders, coarse vacuolar degeneration (arrows), flattened cytoplasm, and cell detachment (arrowheads) were observed in tubular epithelial cells (periodic acid–Schiff stain)