Fig. 1
From: A case report of an M protein-negative patient with POEMS syndrome associated with renal involvement

Pathological changes in renal tissue before treatment (A-D). A1, B1, C2, D1: swelling and proliferation of endothelial cells; A2, B3, C1: “double contour sign”; A3, B2, D2: vacuolar degeneration of endothelial cells (Periodic Acid-Schiff stain are seen by light microscopy; original magnification x400)