Variables | Model 1 | Model 2 | Model 3 |
---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P |
---|
EASIX |
< 2.06 | Ref | | Ref | | Ref | |
≥ 2.06 | 1.47 (1.13–1.91) | 0.004 | 1.44 (1.10–1.88) | 0.009 | 1.42 (1.08–1.88) | 0.012 |
- Model 1 covariates were adjusted for nothing
- Model 2 covariates were adjusted for sepsis, SBP, DBP, respiratory rate, anion gap, 24 h urine output, CCI,and qSOFA
- Model 3 covariates were adjusted for sepsis, SBP, DBP, respiratory rate, anion gap, 24 h urine output, CCI, qSOFA, mechanical ventilation, vasopressors, and nephrotoxic antibiotics
- Models 1, 2 and 3 were derived from logistic regression models
- Abbreviations: EASIX endothelial activation and stress index, AKI Acute kidney injury, OR odds ratio, CI confidence interval, Ref reference, SBP systolic blood pressure, DBP diastolic blood pressure, CCI Charlson comorbidity index, qSOFA Quick sequential organ failure assessment