Variables | Time of measurement | Control Mean ± SD | Intervention Mean ± SD | P-value |
---|---|---|---|---|
-Medication | T1 | 26.20 ± 4.85 | 27.11 ± 4.97 | 0.34* |
 | T2 | 26.14 ± 4.93 | 15.92 ± 5.70 | < 0.001** |
 | T3 | 26.02 ± 4.87 | 18.69 ± 6.04 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
-Activities of living | T1 | 19.23 ± 4.03 | 18.55 ± 4.85 | 0.44* |
 | T2 | 19 ± 4.12 | 10.44 ± 3.61 | < 0.001** |
 | T3 | 19.16 ± 4.18 | 11.36 ± 3.73 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
-Community and follow-up | T1 | 17.60 ± 1.56 | 17.41 ± 1.51 | 0.47* |
 | T2 | 17.37 ± 1.60 | 11.02 ± 1.78 | < 0.001** |
 | T3 | 17.51 ± 1.81 | 11.86 ± 1.58 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
-Feelings related to condition | T1 | 12.23 ± 2.11 | 12.25 ± 1.76 | 0.96* |
 | T2 | 12.06 ± 2.16 | 7.98 ± 1.61 | < 0.001** |
 | T3 | 12.08 ± 2.15 | 8.53 ± 1.44 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
-Treatment and complications | T1 | 28.21 ± 3.37 | 28.59 ± 3.82 | 0.6* |
 | T2 | 28.18 ± 3.29 | 16.02 ± 3.83 | < 0.001** |
 | T3 | 28.16 ± 3.43 | 19.04 ± 4.05 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
-Enhancing QoL | T1 | 23.18 ± 5.33 | 22.51 ± 3.41 | 0.45* |
 | T2 | 22.82 ± 5.38 | 13.18 ± 3.20 | < 0.001** |
 | T3 | 22.86 ± 5.33 | 14.79 ± 3.30 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
-Skin care | T1 | 10.57 ± 2.68 | 11.67 ± 3.11 | 0.06* |
 | T2 | 10.45 ± 2.75 | 6.71 ± 2.24 | < 0.001** |
 | T3 | 10.51 ± 2.70 | 7.37 ± 2.39 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |
Total PLNS | T1 | 137.23 ± 15.82 | 138.10 ± 13.48 | 0.77* |
 | T2 | 136.02 ± 15.97 | 81.28 ± 15.20 | < 0.001** |
 | T3 | 136 ± 16.03 | 91.65 ± 15.21 | < 0.001** |
P-value |  | > 0.05*** | < 0.05*** |  |