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Fig. 1 | BMC Nephrology

Fig. 1

From: The relationship between serum levels of LOX-1, hs-cTnT, NGAL, and renal function, and their diagnostic value in patients with chronic kidney disease: a retrospective study

Fig. 1

ROC Curves For LOX-1, Hs-CTnT, and NGAL. This ROC curve compares the predictive performance of serum levels of LOX-1, hs-cTnT, and NGAL in patients with mild and severe renal dysfunction. The levels of LOX-1 (31.67 ± 4.23 vs. 38.01 ± 3.98), hs-cTnT (133.54 ± 12.79 vs. 158.21 ± 15.62), and NGAL (18.76 ± 3.21 vs. 24.08 ± 4.56) were significantly lower in patients with mild renal dysfunction compared to those with severe renal dysfunction (P < 0.05), indicating a potential relationship between these biomarkers and the severity of renal dysfunction. The AUC values for each biomarker were 0.859 for LOX-1, 0.882 for hs-cTnT, and 0.841 for NGAL, suggesting that all three biomarkers have predictive value for assessing the progression of chronic kidney disease. Among them, hs-cTnT demonstrated the strongest predictive capability, followed by LOX-1 and NGAL

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