Fig. 1

ROC Curves For LOX-1, Hs-CTnT, and NGAL. This ROC curve compares the predictive performance of serum levels of LOX-1, hs-cTnT, and NGAL in patients with mild and severe renal dysfunction. The levels of LOX-1 (31.67ā±ā4.23 vs. 38.01ā±ā3.98), hs-cTnT (133.54ā±ā12.79 vs. 158.21ā±ā15.62), and NGAL (18.76ā±ā3.21 vs. 24.08ā±ā4.56) were significantly lower in patients with mild renal dysfunction compared to those with severe renal dysfunction (Pā<ā0.05), indicating a potential relationship between these biomarkers and the severity of renal dysfunction. The AUC values for each biomarker were 0.859 for LOX-1, 0.882 for hs-cTnT, and 0.841 for NGAL, suggesting that all three biomarkers have predictive value for assessing the progression of chronic kidney disease. Among them, hs-cTnT demonstrated the strongest predictive capability, followed by LOX-1 and NGAL