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Table 3 Subgroup analysis of the association between ApoE genotypes and DKD risk in T2D by albuminuria

From: The impact of PPARγ and ApoE gene polymorphisms on susceptibility to diabetic kidney disease in type 2 diabetes mellitus: a meta-analysis

ApoE genotypes

Microalbuminuria

Macroalbuminuria

Samle size (case/control)

OR

95% CI

I2(%)

Ph

Begg’s test (P)

Egger’s test (P)

Samle size (case/control)

OR

95% CI

I2(%)

Ph

Begg’s test (P)

Egger’s test (P)

ε3/ε4

368/954

0.66

0.44-0.99

0

0.56

0.45

0.4

367/1191

0.95

0.64-1.43a

15.2

0.32

0.45

0.91

ε4/ε4

192/599

0.76

0.16-3.53

0

0.91

0.71

0.69

224/1010

2.18

0.76-6.29

0

0.67

0.31

0.22

ε2/ε2

110/406

2.39

0.55-10.34

0

0.53

1

-

181/875

2.83

0.58-13.9

0

0.48

1

0.91

ε2/ε3

368/954

1.38

0.89-2.13

0

0.81

1

0.99

330/1120

1.43

0.44-4.66a

84.6

<0.001

0.81

0.89

ε2/ε4

346/855

3.32

1.13-9.73

0

0.66

0.22

0.04

181/875

0.7

0.12-4.02

0

0.92

1

0.81

  1. Statistically significant results (p < 0.05) are highlighted in bold
  2. aRandom-effects model was applied
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BMC Nephrology

ISSN: 1471-2369

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