Table 1 Baseline Patients Characteristic

N

112 (83.6%)

22 (16.4%)

^† Mean (SD) Age at TMA diagnosis, years

46.5 ± 16.0

28.9 ± 16.3

 < 0.001

Mean (SD) Age at transplant, years

46.1 ± 14.8

38.5 ± 10.6

0.022

Ethnicity

 White

66 (58.9%)

17 (77.3%)

0.287

 Black

42 (37.5%)

5 (22.7%)

 Other

4 (3.6%)

0 (0.0%)

Gender, Female

56 (50.0%)

15 (68.2%)

0.161

Donor type

 Deceased donor

69 (61.6%)

9 (40.9%)

0.185

 Living unrelated

20 (17.9%)

6 (27.3%)

 Living related

23 (20.5%)

7 (31.8%)

Donor's age, years

43.5 ± 14.9

37.0 ± 13.7

0.038

Donor's terminal Creatinine, mg/dL

1.1 (0.4–4.0)

1.4 (0.5–6.5)

0.540

Highly sensitized

47 (67.1%)

15 (75.0%)

0.592

^‡ HLAi or ABOi transplant (required desensitization)

46 (51.1%)

6 (30.0%)

0.136

^§ Pre-transplant DSA

50 (66.7%)

8 (40.0%)

0.04

Re-transplantation

63 (56.2%)

13 (59.1%)

1

Warm ischemic time, minutes

47.2 ± 24.8

42.5 ± 11.8

0.641

Cold ischemic time, hours

19.7 ± 17.2

10.3 ± 10.8

0.023

Delayed graft function

45 (40.9%)

4 (18.2%)

0.054

Reason for previous graft loss

 TMA

4 (5.3%)

15 (93.8%)

 < 0.001

 ^¶ Acute ABMR

9 (11.8%)

0 (0.0%)

 Chronic ABMR

30 (39.5%)

0 (0.0%)

 BK nephropathy

3 (3.9%)

0 (0.0%)