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Table 2 Univariate and multivariate analysis of factors associated with a composite of graft failure, BPAR and de novo DSA

From: A comparative study on outcomes of ABO-incompatible kidney transplants between robot-assisted vs. open surgery-propensity score-matched analysis: a retrospective cohort study

Factors

    

Univariable

Multivariable

HR

95%CI

 

p-value

HR

95%CI

 

p-value

Open KT

1

  

0.7105

   

0.961

RAKT

0.797

0.241

2.636

 

0.97

0.292

3.229

 

Recipient

        

Mean age, years

0.998

0.968

1.028

0.8786

    

Female gender, n (%)

1.309

0.632

2.712

0.4688

    

Body mass index, kg/m2

1.069

0.985

1.161

0.11

    

Preemptive transplant, n (%)

0.894

0.341

2.344

0.8199

    

Dialysis duration, months

0.995

0.974

1.016

0.6424

    

Retransplantation, n (%)

NA

       

Number of HLA mismatch (ABDR), (range)

1.196

0.94

1.521

0.1453

    

HLA-incompatible KT, n (%)

3.753

1.744

8.074

0.0007

2.889

0.974

8.564

0.056

Rituximab dose (desentization)

   

0.4621

    

<200 mg, n(%)

1

       

>200 mg, n(%)

0.758

0.362

1.587

     

IgM titer (IQR)

1

0.999

1.001

0.6989

    

Pre-transplant DSA, n(%)

3.092

1.475

6.482

0.0028

2.161

0.842

5.547

0.109

Immunosuppressants

        

Induction, n (%)

   

0.021

   

0.671

Basiliximab

1

   

1

   

Thymoglobulin

2.527

1.15

5.553

 

0.78

0.248

2.452

 

Calcineurin inhibitor, n (%)

   

0.8085

    

Tacrolimus

1

       

Cyclosporine

1.28

0.174

9.435

     

Donor

        

Mean age, years

0.992

0.96

1.025

0.6489

    

Female gender, n (%)

0.695

0.335

1.44

0.3277

    

Body mass index, kg/m2

1.1

0.986

1.228

0.089

    

Relation to a recipient, n (%)

   

0.1136

    

Living-related

1

       

Living-unrelated

1.889

0.859

4.154

     

DM, donor

0.583

0.079

4.286

0.5958

    

HTN, donor

0.96

0.424

2.172

0.9211

    

24-h creatinine clearance, mL/min

1.006

0.993

1.018

0.385

    

24-h urine protein, mg/day

0.984

0.967

1.001

0.073

    

Left kidney donation, n (%)

1.524

0.694

3.348

0.2935

    
  1. DM, diabetes mellitus; DSA, donor-specific antibody; HLA, human leukocyte antigen; HTN, hypertension; IQR, Interquartile Range; RAKT, robot-assisted kidney transplantation