Table 2 Univariate and multivariate Cox regression analysis between candidate predictors and survival of IgAN patients with stage 4 CKD
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95%CI) | P | HR (95%CI) | P | |
Gender (F) | 0.775 (0.358–1.676) | 0.52 |  |  |
Age (per 1 year increment) | 0.969 (0.937–1.002) | 0.07 |  |  |
BMI (per 1 kg/m2 increment) | 0.968 (0.877–1.070) | 0.53 |  |  |
MAP (per 1mmHg increment) | 1.020 (0.998–1.042) | 0.07 |  |  |
Hb (per 1 g/L increment) | 0.989 (0.966–1.013) | 0.36 |  |  |
eGFR (per 1 ml/min/1.73m2 increment) | 0.852 (0.763–0.953) | 0.005 | 0.852 (0.756–0.959) | 0.008 |
URBC (per 1/HPF increment) | 0.999 (0.995–1.002) | 0.42 |  |  |
24 h-UP (per 1 g/d increment) | 1.116 (0.945–1.318) | 0.20 |  |  |
UA (per 1µmol/L increment) | 0.999 (0.995–1.004) | 0.73 |  |  |
PTH (per 1pg/mL increment) | 1.000 (0.998–1.002) | 0.93 |  |  |
TC (per 1mmol/L increment) | 1.151 (0.925–1.434) | 0.21 |  |  |
TG (per 1mmol/L increment) | 1.127 (0.811–1.567) | 0.48 |  |  |
Serum IgA/C3 (per 1 increment) | 1.022 (0.806–1.297) | 0.86 |  |  |
C3 deposition intensity (≥ 3+) | 2.759 (1.042–7.304) | 0.04 | 2.955 (1.063–8.220) | 0.038 |
Without Hypertension | 0.855 (0.392–1.865) | 0.69 |  |  |
Use of RASi | 0.478 (0.206–1.110) | 0.09 |  |  |
Use of IS | 0.757 (0.347–1.648) | 0.48 |  |  |
M (1) | 0.225 (0.028–1.788) | 0.16 |  |  |
E (1) | 0.645 (0.192–2.168) | 0.48 |  |  |
S (1) | 1.478 (0.655–3.335) | 0.35 |  |  |
T (1/2) | 2.087 (1.091–3.992) | 0.03 | 2.576 (1.205–5.576) | 0.015 |
C (1/2) | 1.131 (0.615–2.078) | 0.69 |  |  |