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Table 6 Risk factors for post-transplant diabetes mellitus

From: The incidence and risk factors of post-transplant diabetes mellitus in living donor kidney transplantation patients: a retrospective study

Characteristic

Univariable

Multivariable

OR

95% CI

p-value

OR

95% CI

p-value

Age

1.04

1.02, 1.06

< 0.001

1.04

1.01, 1.06

0.002

Gender

   Male

Reference

Reference

    

   Female

1.37

0.70, 2.68

0.354

   

Blood group

   A-

Reference

Reference

    

   A+

0.37

0.08, 1.96

0.202

   

   B-

0.00

NA

0.992

   

   B+

0.56

0.13, 2.91

0.449

   

   AB-

0.00

NA

0.994

   

   AB+

0.00

NA

0.991

   

   O-

0.00

NA

0.993

   

   O+

0.75

0.20, 3.62

0.685

   

Pre-transplantation BMI

   < 18.5

Reference

Reference

    

   18.5–24.9

0.70

0.22, 2.70

0.569

   

   25–29.9

1.27

0.40, 4.85

0.703

   

   30–34.9

1.81

0.53, 7.32

0.367

   

   35 or more

1.50

0.18, 9.62

0.676

   

Post-transplantation BMI

   < 18.5

Reference

Reference

    

   18.5–24.9

1.38

0.32, 9.56

0.696

   

   25–29.9

1.64

0.41, 11.1

0.535

   

   30–34.9

1.95

0.45, 13.6

0.420

   

   35 or more

2.35

0.44, 18.1

0.345

   

Chronic conditions

   HTN

1.23

0.55, 3.02

0.629

   

   Anemia

0.74

0.11, 2.81

0.697

   

   Hyperlipidemia

1.16

0.32, 3.36

0.795

   

   Hepatitis B

0.48

0.03, 2.59

0.484

   

   Hepatitis C

0.00

NA

0.990

   

   Cancer

0.00

NA

0.989

   

   SLE

0.69

0.04, 4.03

0.732

   

   CMV

1.14

0.25, 3.73

0.848

   

Cause of ESKD

   HTN

Reference

Reference

 

Reference

Reference

 

   Glomerulonephritis

0.21

0.05, 0.77

0.017

0.32

0.08, 1.27

0.100

   Graft failure

0.50

0.02, 5.06

0.585

0.66

0.03, 7.24

0.749

   Polycystic kidney disease (ARPKD)

1.50

0.05, 43.2

0.788

3.91

0.13, 121

0.381

   Polycystic kidney disease (ADPKD)

0.19

0.01, 1.44

0.158

0.18

0.01, 1.44

0.153

   Unknown

0.36

0.12, 1.16

0.076

0.48

0.15, 1.65

0.224

   Other

0.13

0.02, 0.57

0.009

0.19

0.03, 0.92

0.045

Type of dialysis

   Not on dialysis

Reference

Reference

    

   Hemodialysis

1.23

0.44, 4.40

0.717

   

   Peritoneal dialysis

1.44

0.37, 6.23

0.605

   

   Duration of dialysis (months)

1.00

0.98, 1.01

0.622

   

   Admission /Baseline serum creatinine

1.00

1.00, 1.00

0.426

   

Type of immunotherapy used

   Tacrolimus + Steroid + MMF

Reference

Reference

    

   Tacrolimus + Steroid

1.57

0.49, 4.30

0.406

   

   Tacrolimus

0.00

NA

0.989

   

   Cyclosporine

0.00

NA

0.992

   

Duration of immunosuppression (all drugs) (years)

0.97

0.81, 1.18

0.792

   

Complications

   UTI

0.45

0.13, 1.20

0.148

   

   CMV

0.61

0.26, 1.31

0.230

   

   BK

0.94

0.33, 2.27

0.890

   

   HCV

0.00

NA

0.988

   

   Polycythemia

0.81

0.04, 4.91

0.846

   

   AKI

1.89

0.40, 6.88

0.361

   

   Perirenal fluid collections

2.05

0.54, 6.50

0.244

   

   Herpes

5.07

0.59, 43.3

0.109

   

   Anemia

0.00

NA

0.990

   

   Hypertension

1.23

0.06, 8.55

0.857

   

Graft rejection episodes

   Stable graft function

Reference

Reference

    

   Acute rejection

0.00

 

0.985