From: Effects of immunosuppressive therapy on renal prognosis in primary membranous nephropathy
 | Total | Conservative group | Immunosuppressive Group | |||
---|---|---|---|---|---|---|
 | HR | p value | HR | p value | HR | p value |
Age (years old) | 1.02 | 0.0003 | 1.02 | 0.0151 | 1.02 | 0.0068 |
Male [n, (%)] | 0.93 | 0.6262 | 0.72 | 0.119 | 1.26 | 0.3304 |
BMI (kg/m2) | 0.94 | 0.0019 | 0.93 | 0.0178 | 0.94 | 0.0402 |
SBP (mmHg) | 1.01 | < 0.0001 | 1.01 | 0.0168 | 1.02 | < 0.0001 |
DBP (mmHg) | 1.02 | 0.0054 | 1.01 | 0.049 | 1.02 | 0.064 |
Diabetes mellitus | 1.40 | 0.2798 | 1.31 | 0.517 | 1.52 | 0.365 |
Hypertension | 1.17 | 0.3127 | 1.22 | 0.3292 | 1.09 | 0.7176 |
Nephrotic syndrome | 1.36 | 0.0466 | 1.95 | 0.0017 | 0.88 | 0.5766 |
RASi | 1.13 | 0.5464 | 0.94 | 0.8348 | 1.35 | 0.2942 |
Other hypotensive drugs | 2.04 | < 0.0001 | 1.86 | 0.0021 | 2.31 | 0.0004 |
Antiplatelets / Anticoagulant drug | 0.70 | 0.0228 | 0.71 | 0.0994 | 0.69 | 0.1166 |
Urate-lowering drugs | 0.68 | 0.2377 | 0.80 | 0.6005 | 0.54 | 0.2331 |
Lipid regulating agents | 0.94 | 0.7803 | 1.23 | 0.4863 | 0.61 | 0.1236 |
Calcium supplements | 1.43 | 0.0274 | 1.33 | 0.1599 | 1.63 | 0.072 |
Stomach protectants | 1.03 | 0.87 | 0.79 | 0.417 | 1.28 | 0.3195 |
*SGLT2i | 0.00 | 0.9919 | 0.00 | 0.9955 | 0.00 | 0.9959 |
WBC | 1.00 | 0.9544 | 1.06 | 0.2222 | 1.03 | 0.3345 |
Hg | 1.00 | 0.722 | 0.98 | 0.0019 | 0.99 | 0.0221 |
PLT | 1.00 | 0.6224 | 1.00 | 0.1601 | 1.00 | 0.1835 |
HbA1c | 1.09 | 0.5517 | 1.02 | 0.8925 | 1.05 | 0.6228 |
Alb | 0.94 | < 0.0001 | 0.92 | < 0.0001 | 0.97 | 0.117 |
TC | 1.13 | < 0.0001 | 1.14 | 0.0001 | 1.13 | 0.0085 |
TG | 1.05 | 0.1275 | 1.01 | 0.8145 | 1.11 | 0.0273 |
HDL-C | 1.16 | 0.0736 | 1.03 | 0.8268 | 1.94 | 0.0011 |
LDL-C | 1.12 | 0.0009 | 1.17 | 0.0003 | 1.05 | 0.3484 |
BUN | 1.09 | 0.1345 | 1.08 | 0.1908 | 1.08 | 0.0472 |
URIC | 1.00 | 0.0115 | 1.00 | 0.8895 | 1.00 | 0.0608 |
Cr | 1.00 | 0.1275 | 1.00 | 0.0813 | 1.00 | 0.8377 |
eGFR | 0.99 | 0.0036 | 0.99 | 0.021 | 0.99 | 0.0794 |
Proteinuria (mg/24-hour) | 1.00 | 0.008 | 1.00 | 0.0059 | 1.00 | 0.3631 |
PLA2Rab | 1.00 | 0.0002 | 1.00 | 0.0005 | 1.00 | 0.1701 |