Table 2 Baseline characteristics of PMN patients in different risk levels
From: Effects of immunosuppressive therapy on renal prognosis in primary membranous nephropathy
|  | Low risk (N = 151) | Moderate risk (N = 113) | High risk (N = 200) | P-value |
|---|---|---|---|---|
Demographics | Â | Â | Â | Â |
Age (years old) | 44.85 ± 13.73 | 55.10 ± 10.73 | 48.24 ± 13.88 | < 0.001 |
Male [n, (%)] | 71 (47.02%) | 72 (63.72%) | 131 (65.50%) | 0.001 |
BMI (kg/m2) | 23.53 ± 3.48 | 24.14 ± 3.52 | 23.53 ± 3.74 | 0.295 |
SBP (mmHg) | 128.82 ± 19.55 | 142.50 ± 22.47 | 140.43 ± 23.26 | < 0.001 |
DBP (mmHg) | 81.40 ± 12.42 | 86.31 ± 14.47 | 86.59 ± 12.86 | < 0.001 |
Comorbidities (%) | Â | Â | Â | Â |
Diabetes mellitus | 8 (5.30%) | 7 (6.19%) | 11 (5.50%) | 0.949 |
Hypertension | 31 (20.53%) | 45 (39.82%) | 76 (38.00%) | < 0.001 |
Clinical symptom (%) | Â | Â | Â | Â |
Nephrotic syndrome | 0 (0.00%) | 82 (72.57%) | 176 (88.00%) | < 0.001 |
Laboratory measurements | Â | Â | Â | Â |
Alb (g/L) | 30.20 (25.60–34.60) | 25.40 (22.10–28.50) | 22.30 (19.88–24.90) | < 0.001 |
Total cholesterol | 6.91 ± 2.20 | 8.04 ± 2.32 | 8.46 ± 2.63 | < 0.001 |
eGFR-EPI (ml/min/1.73m2) | 113.53 (105.11-124.64) | 83.18 (73.30-94.15) | 100.31 (76.10-115.79) | < 0.001 |
Proteinuria (mg/24-hour) | 2347.02 (1525.50-3056.20) | 4972.60 (3622.00-5958.00) | 7079.51 (4772.25–9476.00) | < 0.001 |
PLA2R Ab (RU/ml) | 14.39 (5.00-39.27) | 57.11 (20.00-170.84) | 72.81 (29.90-174.80) | 0.015 |
Comedication | Â | Â | Â | Â |
RASi | 117 (77.48%) | 93 (82.30%) | 152 (76.00%) | 0.426 |
Other hypotensive drugs | 39 (25.83%) | 54 (47.79%) | 107 (53.50%) | < 0.001 |
Antiplatelets / Anticoagulant drug | 71 (47.02%) | 57 (50.44%) | 89 (44.50%) | 0.598 |
Urate-lowering drugs | 14 (9.27%) | 13 (11.50%) | 11 (5.50%) | 0.149 |
Lipid regulating agents | 127 (84.11%) | 96 (84.96%) | 179 (89.50%) | 0.283 |
Calcium supplements | 71 (47.02%) | 59 (52.21%) | 93 (46.50%) | 0.594 |
Stomach protectants | 58 (38.41%) | 47 (41.59%) | 77 (38.50%) | 0.839 |
SGLT2i | 3 (1.99%) | 1 (0.88%) | 2 (1.00%) | 0.653 |