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Table 1 Baseline characteristics of the study population according to the type of glomerular disease

From: Urinary sediment mRNA as a potent biomarker of IgA nephropathy

 

IgAN

(n = 200)

LN

(n = 6)

MCD

(n = 16)

Crescentic GN

(n = 17)

MN

(n = 9)

Healthy control

(n = 76)

Age (years)

42.38 ± 15.97de

39.16 ± 14.42 d

42.68 ± 22.16 d

66.59 ± 8.74 abc

58.78 ± 10.92a

39.43 ± 15.21

Male (n, %)

99 (49.5%)

0 (0.0%)

9 (56.3%)

6 (35.3%)

5 (55.6%)

18 (23.7%)

BMI (kg/m2)

23.89 ± 3.43

22.4 ± 2.76

25.25 ± 3.77

23.52 ± 3.61

24.03 ± 1.63

-

HTN (n, %)

73 (36.5%)

2 (33.3%)

5 (31.3%)

6 (35.2%)

3 (33.3%)

-

DM (n, %)

12 (6.0%)

0 (0.0%)

1 (6.2%)

2 (11.8%)

1 (11.1%)

-

Albumin (g/dL)

3.90 ± 0.53bcde

2.87 ± 0.72a

2.51 ± 0.9ade

3.19 ± 0.48ac

3.20 ± 0.77ac

-

IgA (mg/dL)

305.11 ± 94.99

265.67 ± 117.46

273.06 ± 85.03

290.35 ± 101.09

210.33 ± 66.59

-

Creatinine (mg/dL)

1.32 ± 1.24 d

0.94 ± 0.64 d

1.20 ± 0.90 d

4.18 ± 2.67 abce

0.69 ± 0.21 d

-

eGFR (ml/min/1.73 m2)

80.48 ± 37.23d

95.20 ± 49.81d

87.06 ± 43.45d

24.07 ± 31.38abce

99.24 ± 23.28 d

-

Urine PCR (g/gCr)

1.64 ± 2.04 cef

2.54 ± 2.26cef

9.84 ± 6.79 abdf

2.26 ± 1.13cef

6.89 ± 4.71abdf

0.09 ± 0.06

Urine RBC grade

      

 < 5/HPF

45 (22.5%)

1 (16.7%)

10 (62.5%)

1 (5.9%)

3 (33.3%)

-

 5–9/HPF

28 (14.0%)

1 (16.7%)

4 (25.0%)

2 (11.8%)

1 (11.1%)

-

 10–29/HPF

47 (23.5%)

2 (33.3%)

1 (6.3%)

4 (23.5%)

2 (22.2%)

-

 ≥ 30/HPF

80 (40.0%)

2 (33.3%)

1 (6.3%)

10 (58.8%)

3 (33.3%)

-

  1. IgAN, IgA nephropathy; LN, lupus nephritis; MCD, minimal change disease; Crescentic GN, crescentic glomerulonephritis; MN, membranous nephropathy; BMI, body mass index; HTN, hypertension; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; PCR, protein creatinine ratio; RBC, red blood cell; HPF, high-power field
  2. a: P < 0.05, vs. IgAN; b: P < 0.05, vs. LN; c: P < 0.05, vs. MCD; d: P < 0.05, vs. Crescentic GN; e: P < 0.05, vs. MN; f: P < 0.05, vs. healthy control