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Table 4 Bivariate and multivariable analysis of factors associated with medication adherence among post kidney transplant patients (N = 270) in SPHMMC

From: Medication non-adherence and its associated factors among kidney transplant patients in a large teaching hospital in Ethiopia

Variables

Adherence

COR (95%, CI)

AOR (95%, CI)

P-value

 

Adherent

N(%)

Non-adherent

N(%)

Bivariate

Multivariable

 

Age

   

0.967(0.95–0.997)

1.05(0.964–1.14)

0.28

Age group

≤ 30 years

80(88.9)

10(11.1)

1(0)

1(0)

 

31–45 years

94(82.5)

20(17.5)

0.588(0.26–1.33)

0.442(0.109–1.78)

0.251

> 45 years

47(72.3)

18(27.7)

0.333(0.14–0.77)

0.19(0.016–2.22)

0.185

Marital status

Unmarried

82(89.1)

10(10.9)

1(0)

1(0)

 

Married

139(78.1)

39(21.9)

0.435(0.21–0.92)

0.682(0.22–2.07)

0.499

Duration after transplant

   

0.867(0.78–0.96)

1.17(0.918-1.50)

0.201

Duration after transplant category

< 1 year

62(96.9)

2(3.1%)

1(0)

1(0)

 

1–2½ years

29(74.4)

10(25.6)

0.094(0.019–0.455)

0.303(0.048–1.902)

0.203

2½-5years

94(83.2)

19(16.8)

0.16(0.036–0.709)

0.367(0.057–2.38)

0.293

> 5years

36(66.7)

18(33.3

0.065(0.014–0.294)

0.074(0.007–0.78)

0.031*

Missed follow up

Never

136(93.2)

10(6.8)

1 (0)

1(0)

 

Missed 1 times

37(78.7)

10(21.3)

0.272(0.105–0.703)

0.301(0.10–0.90)

0.032*

Missed 2 times

28(68.3)

13(31.7)

0.158(0.062–0.397)

0.176(0.06–0.513)

0.001*

Missed above 2 times

20(55.6)

16(44.4)

0.092(0.037–0.23)

0.088(0.028–0.278)

< 0.0001**

Reason for adherence

Drug unavailability

58(96.7)

2(3.3)

1(0)

1(0)

 

Drug adverse effect

20(95.2)

1(4.8)

0.69(0.06-8.0)

0.87(0.064–11.74)

0.917

Financial shortage

13(76.5)

4(23.5)

0.112(0.019–0.679)

0.175(0.024-1.28)

0.086

Forgetfulness

123(55.7)

41 [12]

0.103(0.024–0.442)

0.104(0.021–0.523)

0.006*

Other reason

7(87.5)

1(12.5)

0.241(0.019–3.02)

0.85(0.058–12.36)

0.905

  1. AOR: Adjusted Odds ratio; COR: Crude Odds ratio; CI: Confidence interval; N-number of patients; P-Probability; SPHMMC- Saint Paul`s Hospital Millennium Medical College
  2. * Statistically significant