Figure 4

PodoTrsp ^-/- and control ( Trsp ^L/L ) mice have similar mesangial matrix volumes. A, Percent of mesangial matrix in glomeruli from control and PodoTrsp^-/- mice after 6 months of diabetes (or after vehicle injection). Control mice, vehicle n = 6, STZ n = 6; PodoTrsp^-/- mice, vehicle n = 6, STZ n = 6. B-E, PAS staining of glomeruli.